These clinically validated skincare products use biomimetic exosomes for accelerated skin renewal, exclusively for men.

Caldera + Lab, the premium high-performance skincare brand for men, today announced the launch of two groundbreaking products: The Great, a clinically advanced anti-aging serum for rapid skin renewal, and The Hydro Layer, a lightweight anti-aging moisturizer. Both products are powered by Caldera + Lab’s patent-pending biomimetic exosomes specifically engineered for men’s skin to improve absorption of powerful plant-based ingredients. With billions of exosomes in each application, this first-to-market technology delivers 20 times the amount of active ingredients deep within men’s skin for visible results.

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A breakthrough anti-aging serum, The Great (left) rapidly reduces signs of aging, visibly improving the appearance of lines and wrinkles, evening skin tone, and lifting and firming skin. The Hydro Layer (right) is a weightless, anti-aging moisturizer designed to firm and fortify, visibly reduce lines and wrinkles, minimize pores, and hydrate men’s skin at every level.

Backed by dermatological and clinical research, men’s skin is distinctly shaped by testosterone-driven biology. On average, it is 25% thicker, produces more oil, is more collagen-dense, and ages with deeper wrinkles. These innovations are formulated to deliver deeper ingredient penetration, promote skin renewal, and address damage caused by lifestyle, environmental stressors, and aging.

Patent-Pending Exosome Technology

Caldera + Lab’s patent-pending exosome technology utilizes biomimetic exosomes - nanoparticles 1,000 times smaller than a skin pore - engineered for men’s skin. This advanced delivery system encapsulates plant-based actives and guides them to the right layer of skin, where they can work most effectively.

B³OS+™: Caldera + Lab’s R&D Approach

At the core of all Caldera + Lab products is B³OS+™ (biology, biomimetics, and biotechnology), the first and only clinical R&D framework built for men’s skin. It begins with an understanding of men’s skin biology and its structural differences, combining this with plant-based ingredients that mimic natural pathways to target concerns unique to men. Advanced biotech practices further enhance the efficacy of each product to deliver powerful formulations for visible, clinically backed results.

“These two products mark the next step in our mission to deliver high-performing, clinically proven skincare for men,” said Jared Pobre, founder and CEO of Caldera + Lab. “After years of research and clinical testing, we’ve engineered proprietary ingredients that set a new standard in men’s skincare. By combining the powers of plant biotechnology with our own exosomes, we can deliver active ingredients with unprecedented precision and efficacy, outperforming ingredients like collagen and retinol. This innovative approach reflects our commitment to bringing uncompromising, science-backed products to men.”

The Great: Formulation Highlights & Usage

A breakthrough anti-aging serum, The Great rapidly reduces signs of aging, visibly improving the appearance of lines and wrinkles, evening skin tone, and lifting and firming skin.

• Each application delivers 150 billion biomimetic exosomes that encapsulate plant-based actives, delivering them deeper into the skin.
• Collagen amino acids support firmness and strengthen the skin barrier, while ultra-low molecular weight hyaluronic acid provides powerful, lightweight hydration, ideal for men’s skin.
• Adaptobiome™, a blend of probiotic ferments, adaptogenic botanicals like Ashwagandha and Holy Basil, and microalgae-derived Astaxanthin, helps balance the microbiome and protect skin from environmental stressors.
• Usage: For best results, apply twice daily, morning and evening, after cleansing.

The Hydro Layer: Formulation Highlights & Usage

The Hydro Layer is a weightless, anti-aging moisturizer designed to firm and fortify, visibly reduce lines and wrinkles, minimize pores, and hydrate men’s skin at every level.

• Powered by biomimetic exosomes and peptide growth factors, this formula goes far beyond surface hydration, visibly renewing skin and targeting signs of aging for a more youthful appearance.
• A next-gen hydro complex of hyaluronic acid, polyglutamic acid, and ceramides delivers lasting hydration and reinforces the skin barrier for improved skin resilience.
• The lightweight, gel-cream texture absorbs quickly for a shine-free, non-greasy finish.
• Usage: Apply twice daily, morning and evening, after cleansing and serum application.

Launching alongside these innovations is a refreshed brand identity, an elevated look and feel that reflects Caldera + Lab’s focus on science-driven design, sustainability, and simplicity. This new aesthetic underscores the brand’s evolution while staying true to its mission of creating high-performance skincare tailored to men.

“Our new visual identity reflects our philosophy of merging science with a modern aesthetic that speaks to men who value performance,” Pobre added. “It’s a clean, elevated look that embodies purpose and progress, while delivering on our commitment to sustainability. We also believe in the importance of transparency to help men better understand the benefits of responsible skincare. We’re excited for this next chapter and look forward to continuing our path of meaningful, lasting change with an innovation-driven approach to men’s self-care.”

The Great (30ml) - $110 and The Hydro Layer (55ml) - $65 are now exclusively available at calderalab.com.

About Caldera + Lab

Caldera + Lab, founded in 2019, is a pioneering leader in science-backed skincare, setting a new standard in men’s self-care. Designed specifically for men, the brand offers high-performance, clinically proven products rooted in cutting-edge biotech and proprietary ingredient innovation to enhance skin and hair health. Grounded in the belief that self-care is a vital pillar of overall wellbeing—alongside fitness and nutrition—Caldera + Lab supports men in optimizing their health span and daily routines. Sustainability, scientific integrity, and social impact are central to the company’s mission, guiding every aspect of its operations. The ultimate goal: to leave both customers and the planet better than they were found. For more information visit calderalab.com.

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"These two products mark the next step in our mission to deliver high-performing, clinically proven skincare for men,” said Jared Pobre, founder and CEO of Caldera + Lab.