As filed with the Securities and Exchange Commission on May 04, 2001.
                                                       Registration No. 333-____

================================================================================
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                -----------------

                                    FORM S-3
                          REGISTRATION STATEMENT UNDER
                           THE SECURITIES ACT OF 1933

                                -----------------

                      COMMODORE APPLIED TECHNOLOGIES, INC.
             (Exact name of Registrant as specified in its charter)

            Delaware                                      11-3312952
 (State or other jurisdiction of           (I.R.S. Employer Identification No.)
  incorporation or organization)
                                -----------------

                                SHELBY T. BREWER
          Chairman of the Board, President and Chief Executive Officer
                      Commodore Applied Technologies, Inc.

  2121 Jamieson Avenue, Suite 1406             2121 Jamieson Avenue, Suite 1406
Alexandria, VA 22314 (703) 567-1284          Alexandria, VA 22314 (703) 567-1284
 (Address, including zip code, and        (Name and address, including zip code,
telephone number, including area code,        and telephone number, including
 of registrant's principal executive          area code, of agent for service)
           offices)

                                -----------------
                          Copies of Communications to:
                            Daniel B. Nunn, Jr., Esq.
                                McGuireWoods, LLP
                              Bank of America Tower
                        50 North Laura Street, Suite 3300
                             Jacksonville, FL 32202
                                 (904)-798-2654
                                -----------------
        APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC:

           From time to time as described in the prospectus after the
                 effective date of this Registration Statement.
                                -----------------

         If the only securities being registered on this Form are being offered
pursuant to dividend or interest reinvestment plans, please check the following
box. [ ]

         If any of the securities being registered on this Form are to be
offered on a delayed or continuous basis pursuant to Rule 415 under the
Securities Act of 1933, other than securities offered only in connection with
dividend or interest reinvestment plans, check the following box. [X]

         If this Form is filed to register additional securities for an offering
pursuant to rule 462(b) under the Securities Act, please check the following box
and list the Securities Act registration statement number of the earlier
effective statement for the same offering. [ ]

         If this Form is a post-effective amendment filed pursuant to Rule
462(c) under the Securities Act, check the following box and list the Securities
Act registration statement number of the earlier effective statement for the
same offering. [ ]

         If delivery of the prospectus is expected to be made pursuant to Rule
434, please check the following box. [ ]




                         CALCULATION OF REGISTRATION FEE
=========================================== ====================== ==================== ======================= ====================

                                                                        Proposed               Proposed
                 Title of                          Amount                maximum               maximum               Amount of
       securities to be registered                  to be            offering price           aggregate            registration
                                                registered(1)           per share           offering price              fee
------------------------------------------- ---------------------- -------------------- ----------------------- --------------------

                                                                                                         
Common Stock, par value $.001 per share       19,241,667 shares        $ 0.22 (2)            $ 4,233,167             $ 1058.29
=========================================== ====================== ==================== ======================= ====================


----------------------------

(1)    Pursuant to Rule 416 under the Securities Act of 1933, as amended (the
       "Securities Act"), the number of shares of common stock, par value $0.001
       per share (the "Common Stock"), of Commodore Applied Technologies, Inc.
       (the "Company") being registered shall be adjusted to include any
       additional shares which may become issuable as a result of stock splits,
       stock dividends, or similar transactions.

(2)    Computed in accordance with Rule 457(c) under the Securities Act solely
       for the purpose of calculating the total registration fee. Based on the
       average of the high and low prices (rounded to the nearest cent) of the
       Common Stock as reported on the American Stock Exchange on April 30,
       2001.
                                -----------------
         The Registrant hereby amends this Registration Statement on such date
or dates as may be necessary to delay its effective date until the Registrant
shall file a further amendment which specifically states that this Registration
Statement shall thereafter become effective in accordance with Section 8(a) of
the Securities Act of 1933 or until the Registration Statement shall become
effective on such date as the Commission, acting pursuant to said Section 8(a),
may determine.



                                TABLE OF CONTENTS

                                                                          Page
                                                                          ----
Risk Factors...................................................................1
Forward-Looking Statements....................................................10
About Commodore Applied Technologies..........................................11
Use Of Proceeds...............................................................13
Selling Stockholders..........................................................13
Plan Of Distribution..........................................................17
Legal Matters.................................................................18
Experts.......................................................................18
Where You Can Find More Information...........................................19


SET is a trademark of Commodore Applied Technologies, Inc.



                                  RISK FACTORS

         You should carefully consider the risks described below before deciding
to invest in Commodore Applied Technologies, Inc.'s (the "Company") common
stock. The risks and uncertainties we describe below are the material risks that
we face. If any of the possible events described below actually occur, our
business, financial condition or results of operations could be materially
adversely affected. If that happened, the trading price of our common stock
could decline, and you could lose all or part of your investment.

We have a history of losses from operations and we may continue to incur losses
in the future, which could adversely affect the value of your investment.

         We have experienced significant operating losses since our inception,
and we may continue to incur losses in the future, which could adversely affect
the value of your investment. We had net losses of $5,643,000 during 1996,
$15,694,000 during 1997, $13,353,000 during 1998, $3,985,000 during 1999, and
$11,441,000 during 2000. Our losses have resulted from a combination of:

         o    significant investments in our research and development
              activities;

         o    large expenditures for infrastructure to support our anticipated
              future growth;

         o    significant costs associated with our commercialization
              activities;

         o    lack of sufficient revenues due to significant delays in our
              obtaining material project contracts from potential governmental
              and private-sector customers; and

         o    general and administrative expenses.

         Until we are able to begin additional large projects for our Solvated
Electron Technology (the "SET technology"), the timing of which is uncertain, we
may continue to experience losses. We may incur operating losses in the future
due primarily to:

         o    continuing expenditures for our product development and
              commercialization activities;

         o    delays in obtaining, or the inability to obtain, material project
              contracts from potential governmental and private-sector
              customers;

         o    investments in complementary products and technologies; and

         o    costs associated with expansion of our environmental management
              services business.

         As a result of these losses, as of December 31, 1999 and 2000, we had
an accumulated deficit of approximately $47,248,000 and $58,689,000,
respectively. In an attempt to control our losses we undertook certain actions
in 1998, 1999 and 2000 resulting in the reduction of our workforce, the closing
of ancillary office locations and the elimination of all non-core business
activities. Even though we have taken these steps, we still may not be able to
operate profitably in the future.

Our cash needs are significant, and we will likely need additional funding in
the future. If adequate funds are not available, we may have to delay, scale
back or eliminate one or more of our development programs, which could have a
material adverse effect on our ability to become profitable in the future.

         With the exception of our subsidiary, Dispute Resolution Management,
Inc. ("DRM"), our monthly operating expenses currently exceed our cash revenues
by approximately $200,000. We have required and will require substantial working


                                       1


capital to support our ongoing operations. If adequate funds are not available,
either from periodic distributions from our DRM subsidiary or external sources,
we may be required to delay, scale back or eliminate one or more of our
development programs or certain aspects of our operations (in addition to those
we have already curtailed), which could have a material adverse effect on our
ability to become profitable in the future. In addition, we may need to obtain
additional funds by entering into arrangements with collaborative partners or
others that may require us to relinquish rights to our technology that we would
not otherwise relinquish, or to grant licenses to third parties to commercialize
our technology that we would otherwise seek to develop ourselves.

As a result of our working capital deficiencies, our accountants' report on our
fiscal year 2000 financial statements contains a "going concern" qualification,
in which our accountants express doubt about our ability to continue as a going
concern, absent additional financing.

         Prior to our initial public offering, Commodore Environmental Services,
Inc., the owner of approximately 16.9% of our outstanding common stock, had
provided financing for all of our activities in the form of direct equity
investments and loans. Since the consummation of our initial public offering in
July 1996, we have experienced periodic working capital shortages. As a result
of these working capital shortages, we were required to raise additional capital
through private placements of our preferred stock and common stock.

         Notwithstanding our prior financing, we expect that we will require
significant additional capital either in the form of debt or equity in the near
future to support our operations. Moreover, we may be required to redeem shares
of our Series E and Series F convertible preferred stock under the terms of
those securities and, in light of our current financial position, we may not
have sufficient cash available to redeem those shares and may need to obtain
additional outside financing. In addition, we have a repurchase obligation of
$14.5 million with respect to a portion of our common stock we issued in
connection with our recent acquisition of DRM. In light of our current financial
position we may not have sufficient cash available to satisfy this repurchase
obligation and may need to obtain additional outside financing. Outside
financing could involve a sale of our securities to investors who may require
equal or more favorable terms than those we have agreed to in the past. We may
not be able to obtain any additional financing on acceptable terms, or at all.

If we default on our $14.5 million repurchase obligation, we would be subject to
losing all of our equity interest in DRM capital stock as well as forfeiting up
to an aggregate of 10,750,000 shares of our common stock.

         To secure our commitment to obtain final stockholder approval of the
DRM acquisition by no later than December 1, 2000, the issuance of shares of our
common stock in connection with the DRM acquisition, and to secure our $14.5
million repurchase obligation and certain other covenants we made under the DRM
stock purchase agreement, we have pledged to Mr. William J. Russell and Ms.
Tamie P. Speciale our entire 81% equity interest in DRM. If final stockholder
approval of the DRM acquisition and the issuance of up to 16,500,000 shares of
our common stock in connection with the DRM acquisition is timely obtained, and
we satisfy by September 30, 2001 our $14.5 million repurchase obligation (or
this obligation is waived), then 50% of the pledged equity will be released to
us from this pledge. Our pledge of the balance of our equity interest in DRM
will terminate at such time as we pay or issue, as the case may be, to Mr.
Russell and Ms. Speciale through the quarter ending December 1, 2003, pursuant
to the cash earn out and any short-fall liability, a total of either $10.0
million in cash, a number of shares of our common stock equal to $10.0 million
or any combination of cash or shares of our common stock equal to $10.0 million.

         In the event that by September 30, 2001 we are unable to fully
discharge our $14.5 million repurchase obligation to DRM and the DRM
stockholders, then Mr. Russell and Ms. Speciale (acting on their own behalf and
on behalf of certain other parties) may foreclose on all of the shares of DRM
capital stock that we recently purchased. They may also retain, as liquidated
damages, a number of shares of our common stock equal to 1,000,000 shares plus
50% of the difference between 9,500,000 shares and the number of shares of our
common stock that we purchased or arranged to be purchased from the DRM
stockholders, prior to September 30, 2001, under our purchase option. In
addition, Mr. Russell and Ms. Speciale may retain the 5,000,000 shares of our
common stock which we issued to them in consideration for our option to acquire
from them the remaining 19% equity interest in DRM, and they, in conjunction
with the other holders of warrants to purchase an aggregate of 1,000,000 shares
of our common stock granted in connection with this acquisition, may retain
these warrants.


                                       2


         The loss of our DRM subsidiary would have a material adverse effect on
our business and prospects, including our ability to obtain financial support.

Our SET technology has limited experience on a large-scale commercial basis.
Therefore, we may never realize a profit from the SET technology.

         Our SET technology has limited experience on a large-scale basis and
may never perform successfully on a scale necessary for it to be profitable. As
a result, we cannot predict all of the difficulties that may arise in the
application of our SET technology on a large-scale basis. In addition, not all
of the results of the tests we conducted on our SET technology have been
verified by an independent testing laboratory. Thus, it is possible that this
technology may require further research, development, design and testing, as
well as regulatory clearances, before it can be further commercialized on a
large scale. If we encounter difficulties in testing our SET technology on a
large-scale basis, we may not be able to successfully demonstrate our SET
technology to regulatory authorities from whom we may need to obtain additional
permits in order to operate our business successfully. Additionally, our ability
to operate our business successfully will depend on a variety of factors, many
of which are beyond our control, including:

         o    competition from companies with greater financial and other
              resources than we have;

         o    cost and availability of supplies that we use;

         o    changes in governmental initiatives and requirements that affect
              our technologies and services;

         o    changes in regulatory requirements that apply to our business; and

         o    costs associated with equipment repair and maintenance.

We may not be able to obtain any further collaborative agreements, licenses or
project contracts or maintain those we do have, which may significantly
adversely affect our ability to generate profits in the future.

         Our business is largely dependent on entering into collaborative joint
working arrangements with established engineering and environmental companies,
or entering into joint venture agreements involving the application of our
technologies. If we are not able to enter into these types of arrangements or
agreements, our ability to generate profits in the future could be significantly
adversely affected. To date, only one of our operating subsidiaries and its
collaborative joint working partners have been awarded material project
contracts. We may not be able to enter into any other definitive joint project
arrangements or joint venture collaborative agreements. Even if we are able to
enter into these types of arrangements or agreements, they may not be on terms
and conditions that are sufficiently beneficial to us, or may not enable us to
generate profits. If we are not able to enter into commercially attractive
collaborative working arrangements in the future, we may have to license our
technologies to third parties that are not affiliated with us. We may not be
able to enter into these types of license arrangements. Even if we do, we may
not earn any income from these arrangements. In addition, our existing project
contracts, and any project contract that may be awarded to us and/or any of our
joint working partners in the future, may be curtailed, delayed, redirected or
terminated at any time. Problems or delays that we experience on any specific
project could materially adversely affect our business and financial condition.

We may not be able to compete successfully in the environmental services
industry, which could result in a loss of market share and diminish our brand
recognition.

         Many potential users of our SET technology have already invested
substantial funds in other forms of environmental remediation technology,
including incineration, plasma arc, vitrification, molten metal, molten salt,
chemical neutralization, catalytic electrochemical oxidation and supercritical
wet oxidation. It is possible that these competing technologies may be perceived
to have, or may actually have, certain advantages over our technology for
certain industries or applications, which could adversely affect our ability to
compete successfully in the environmental services industry. Our growth and
future financial performance will depend on our ability to demonstrate to
prospective collaborative partners and customers the advantages of our


                                       3


environmental technology over other technologies. We may not be successful in
this effort.

         Competition in the environmental services industry is intense. The
industry is dominated by large companies such as Bechtel, Westinghouse, Foster
Wheeler and ICF Kaiser, among others. These companies are called upon to serve
as primary contractors and consultants on a large portion of the Superfund,
federal and state government, Department of Energy and Department of Defense
projects. Additionally, many smaller engineering firms, construction firms,
consulting firms and other specialty firms have entered the environmental
services industry in recent years, and additional firms can be expected to enter
the industry in the future. Many of our competitors in the environmental
services industry have significantly greater financial resources and more
established market positions than we do. We may not be able to compete with
these companies. In addition, other firms may expand into or develop expertise
in the areas in which we specialize.

We face significant competition for new business opportunities, and we may not
be able to compete successfully for new business or retain our existing clients.

         The market for our consulting services is highly competitive, and we
face competition from many other providers of consulting services. Our
competitors range from large organizations, such as national accounting firms
and the large management consulting companies that offer a full range of
consulting services, to small firms and independent contractors that provide
only one specialized service. Some of our competitors have significantly more
financial and marketing resources, larger professional staffs or are more widely
recognized. There are few barriers to entry into the consulting business. As the
number of our competitors increases, we cannot assure that we will be able to
continue to compete successfully for new business opportunities or retain our
existing clients.

We are subject to the risk of professional liability that could expose us to
liability in excess of our insurance limits and could injure our reputation.

         Many of our engagements involve complex analysis and the exercise of
professional judgment. As a result, we are subject to the risk of professional
liability. Often, our engagements involve matters that, if resolved unfavorably,
may have severe impact on the client's business, cause the client substantial
monetary loss or prevent the client from pursuing business opportunities.
Therefore, if we fail to perform to the client's satisfaction, the client may
threaten or bring lawsuit against us, claiming we performed negligently or
otherwise breached our obligations to the client. Any claim by a client against
us could expose us to liability in excess of our insurance limits and could
severely injure our reputation.

Our environmental financial settlement consulting business is seasonal and might
affect our revenues during the third quarter of each year.

         We may experience a reduced level of business during a portion of the
third quarter primarily because many members of our professional staff and key
contacts at our clients take vacations during the summer.

Our environmental financial settlement consulting business is subject to
technological change that may prevent us from remaining current with our
technological resources and may adversely affect our business, results of
operations and financial condition.

         We regularly develop solutions for our clients by using information
technology, electronic document management techniques, the Internet and other
state-of-the-art technology. Many of these technologies have only recently
emerged, will rapidly change and may become obsolete as new technologies appear.
Our future success will depend upon the ability of professionals to remain
current with the rapid changes in the technologies we use in our business and to
learn quickly to use new technologies as they emerge. If our professionals fail
to do this, we could be at a competitive disadvantage. Our competitors may gain
exclusive access to improved technology, which could put us at a competitive
disadvantage. Our clients' or prospective clients' preferences for technology
solutions may change. If we cannot adapt to these changes, our business, results
of operations and financial condition are likely to be adversely effected.


                                       4


We may be adversely affected by extensive environmental regulations that may
result in our incurring significant additional costs and expenses for
compliance, and we could be subject to fines or other penalties for failure to
comply with those regulations.

         The scope and nature of environmental regulation, at the federal, state
and local levels, has expanded dramatically in recent years, and certain
regulations impose stringent guidelines on companies that generate, and handle
hazardous materials, as well as other companies involved in various aspects of
the environmental services industry. Any future expansion or changes in
environmental regulation may result in our incurring additional costs for
equipment, retraining, development of new remediation plans, handling of
hazardous materials and other costs. In addition, we could be liable for
substantial costs and damages (including penalties and fines) associated with
environmental remediation, including investigation, cleanup and natural resource
damages.

         As our environmental technology is commercialized, we may be required
to obtain environmental liability insurance in the future in amounts greater
than those we currently maintain. This type of insurance may not provide
coverage against all claims made against us. In addition, as the cost of
cleaning or correcting environmental hazards can be extremely high, even if it
is determined that we are liable for costs that are covered by our insurance,
any coverage we have may not be adequate to pay the entire cost. If that occurs,
we may be responsible for paying costs in excess of our insurance coverage,
which may significantly reduce working capital necessary to fund our operations.

Our future success may depend on continued environmental regulation in certain
areas, the relaxation of which may result in reduced demand for our services
and, in turn, have a material adverse effect on our stream of revenue.

         Any relaxation of environmental regulation may result in a decline in
demand for environmental services and, in turn, adversely affect our financial
condition. The growth of the environmental services industry has been largely
attributable to, and tracks, the increase in environmental regulation since the
1970s. The demand for environmental services has been largely the result of
facility owners attempting to comply with, or avoid liability under, existing or
newly imposed environmental regulations at the federal, state and local levels.
Because of the burden imposed on the industry in complying with such
regulations, efforts have been made by various groups to seek the relaxation or
repeal of certain environmental regulations. While these efforts to relax
environmental regulation have been largely unsuccessful to date, the scope or
growth of environmental regulation may be curtailed in the future.

We are dependent upon the spending levels of governmental and industrial
entities, the reduction of which could adversely affect our stream of revenue.

         Any curtailment or delays in spending for environmental services by
governmental agencies or industrial entities can be expected to have a material
adverse effect on the environmental services industry and on our operations and
prospects. Because of the nature of sites requiring environmental services, the
growing public emphasis on environmental matters and the cost of environmental
services, governmental agencies and large industrial entities have already spent
a significant portion of all funds budgeted for environmental services. While
governmental agencies and industrial entities may seek reimbursement by third
parties in various cleanups, most Superfund cleanups, as well as weapons and
other nuclear facility cleanups, involve significant spending by governmental
agencies. As budget constraints, emphasis on employment, international
competition and other considerations grow, certain governmental agencies and
industrial entities may choose to delay or curtail expenditures for
environmental services.

Our business is heavily dependent upon contracts to provide services for the
Department of Energy. The failure to renew those contracts or to replace them
will result in a material reduction of our revenues.

         We have received a significant portion of our revenues during the past
two years from contracts in which we have provided services to one client, the
Department of Energy. Our failure to renew those contracts or to replace them
will result in a material reduction of our revenues. Revenues from our contract
to provide technical management support services to the Department of Energy for
the opening and operation of the Waste Isolation Pilot Plant near Carlsbad, New
Mexico constituted approximately 62% of our total revenues in 1999 and 56% of
our total revenues in 2000. This contract ended on December 31, 2000, and the
Company has been unsuccessful with replacing this contract volume in Commodore

                                       5


Advanced Sciences, Inc. ("Advanced"), our engineering subsidiary to date.
Revenues from our contract to provide technical, engineering and scientific
support for the closedown and cleanup of the Department of Energy's facility at
Rocky Flats, Colorado accounted for approximately 22% of our total revenues in
1999 and 7.2% of our total revenues for 2000. The Rocky Flats contract has been
extended and will expire on June 30, 2003. In order for us to replace the
revenues attributable to these large projects, we must secure one or more large
projects or a large number of smaller projects. We may not be able to adequately
replace these projects with other projects that will produce as much revenue. If
we fail to do so, our revenues will be materially reduced and your investment
will be materially adversely affected. Furthermore, we may continue to be
dependent on a small number of major customers for a significant portion of our
revenues.

Our goodwill exceeds our net worth and equals approximately 74% of our total
assets. If we were required to accelerate amortization of our goodwill, we could
show negative stockholders' equity and report significant losses in future
years, which could have a material adverse effect on the value of your
investment.

         As a result of our recent acquisition of DRM, we have recorded
approximately $25.1 million of goodwill, representing the difference between the
fair value of the assets we received in the acquisition and the consideration we
paid for those assets. This goodwill equals approximately 67% of our total
assets. Our goodwill is now 3.2 times larger than our stockholders' equity.
Currently, we plan to amortize the goodwill we recorded in the acquisition of
DRM over 20 years, or at a rate of $1.26 million per year. This will be
reflected as a non-cash charge against earnings. Earnings in later years could
be affected if we determine that the remaining balance of goodwill is impaired
and, thus, should be amortized over a shorter life or expensed immediately. This
acceleration could cause us to report negative stockholders' equity and to
report significant losses in future years and, thereby, have a material adverse
effect on the value of your investment.

The mechanisms to protect our current intellectual property may not be adequate
to protect us from infringement by others, which could adversely affect our
competitive advantage. Also, we cannot assure that our business does not
infringe on the proprietary rights of others, which could require us to
discontinue some or all of our operations.

         We are highly dependent upon proprietary technology and seek to protect
our technology through a combination of patents, licenses and trade secrets. If
the mechanisms to protect our intellectual property currently in place or to be
obtained is insufficient to protect us from infringement by others, we could
lose any competitive advantages that we may have in our markets. In addition, if
we are found to be infringing on the proprietary rights of others, we may have
to discontinue some or all of our operations. Any of these circumstances could
materially adversely affect our ability to generate profits in the future.

         We have 68 patents pending and have 35 patents issued for certain
proprietary aspects of our technology and processes in the United States and
other countries. Our success depends, in large part, on our ability to obtain
additional patents, protect the patents that we currently own, maintain trade
secrecy protection and operate without infringing on the proprietary rights of
third parties. The patents that we currently own are improvement patents, which
are more difficult to monitor for infringement than those that would be
contained in a patent covering a pioneering invention or technology. Our pending
patent applications may not be approved; we may not develop any additional
proprietary technology that is patentable; any patents issued to us may not
provide us with competitive advantages and may be challenged by third parties;
and the patents of others may have an adverse effect on our ability to conduct
our business. Furthermore, others may independently develop similar or superior
technologies, duplicate elements of our technologies, or design around our
technology.

         In the future, we may need to acquire licenses to, or to contest the
validity of, issued or pending patents of third parties. Any license acquired
under the patents of third parties may not be made available to us on acceptable
terms, or at all. In addition, we could incur substantial costs in defending
ourselves in suits brought against us for alleged infringement of another
party's patents or in defending the validity or enforceability of our patents.
In addition to patent protection, we also rely on trade secrets, proprietary
know-how and technology, which we seek to protect, in part, by entering into
confidentiality agreements with our prospective working partners and
collaborators, employees and consultants. These agreements may be breached, and

                                       6


we may not have adequate remedies for any breach. In addition, our trade secrets
and proprietary know-how may otherwise become known or be independently
discovered by others.

Our acquisition program, that includes our recent acquisition of DRM, poses
special risks and financial consequences to us. Our failure to adequately
protect our business from these risks and financial consequences could place
significant strains on our management and working capital and adversely affect
your investment.

         As part of our growth strategy, we may seek to acquire or invest in
complementary (including competitive) businesses, products, or technologies,
which involve numerous risks including:

         o    difficulties in the assimilation of the acquired operations,
              technologies and products:

         o    diversion of management's attention from other business concerns;
              and

         o    potential departures of key employees of the acquired company.

         Any of these risks could materially adversely affect our business,
financial condition and results of operations, thereby adversely affecting the
value of your investment.

         In August 2000, we completed the acquisition of 81% of the outstanding
stock of DRM. Although we believe we have nearly completed the integration of
DRM into our business, we have not yet realized all the benefits we expect to
achieve from the acquisition. We cannot assure you that we will ever realize
these benefits. Our management team's attention may be diverted from seeking new
acquisitions or other business opportunities if they are forced to devote
significant time to enhancing client recognition of DRM's service offerings or
integrating future operations. This could have a materially adverse effect on
our business prospects and results of operations.

         Furthermore, if we successfully identify acquisitions in the future,
completing these acquisitions may result in:

         o    new issuances of our stock that may be dilutive to current owners;

         o    increases in our debt and contingent liabilities; and

         o    additional amortization expenses related to goodwill and other
              intangible assets.

         We continue to explore potential acquisitions. We may not be able to
identify, successfully complete or integrate potential acquisitions in the
future. However, even if we can, we cannot assure that any acquisitions will
have a positive impact on our business or operating results.

We may be liable for any short-falls pursuant to the cash earn out term of the
DRM acquisition.

         The sole shareholders of DRM, Mr. William J. Russell and Ms. Tamie P.
Speciale, are entitled to receive quarterly earn out distributions equal to 35%
of the cash flow of DRM over the period commencing as of September 1, 2000 and
ending December 31, 2005. The aggregate total of these earn out distributions is
not to exceed approximately $37.1 million. We agreed that if DRM has not
distributed to Mr. Russell and Ms. Speciale a total of $10.0 million in cash in
earn out payments by December 31, 2003, we will be liable to make up any
short-fall in an amount equal to the difference between $10.0 million and the
actual cash distributed to them pursuant to these payments. We can satisfy, at
our sole option, this short-fall liability through either a cash payment or, by
issuing to Mr. Russell and Ms. Speciale additional shares of our common stock
valued at the market price of our shares at the time of issuance. If this
obligation requires us to issue more than 2,000,000 shares of our common stock,
we have the right to defer the issuance of any shares in excess of 2,000,000
shares until December 1, 2005, based on the market price at that later date.


                                       7


The loss of our senior management or other key personnel and our failure to
adequately replace them could cause our development and marketing efforts to be
delayed or suspended indefinitely, or cause our client relationships to suffer
or to cease to exist. Any of these circumstances could significantly decrease
the value of your investment.

         Our success depends to a significant extent upon the performance of
senior management and other key employees and on our ability to continue to
attract and retain highly qualified personnel. If any of our senior management
personnel or other key employees were to leave our Company and we were not able
to replace them with other qualified personnel, the further development of our
technology could be significantly delayed or suspended indefinitely, our
marketing efforts could be adversely affected, and our relationships with
certain clients could suffer or to cease to exist.

         As of the date of this prospectus, all the employment agreements with
our senior executive officers of the Company either have expired by their terms
and have not been renewed by us or, in the case of the employment agreement
between the Company and Kenneth L. Adelman, former Executive Vice
President--Marketing and International Development, have been mutually cancelled
and have no further force and effect. Thus, any of our employees could leave the
Company at any time. If any of the members of our senior management become
unable or unwilling to continue in their present roles, or if they decide to
terminate their respective positions and to enter into competition with us, our
operations and prospects could be adversely affected. Competition for highly
skilled employees with technical, management, marketing, sales, product
development and other specialized training is intense. We may not be successful
in attracting and retaining any additional qualified personnel in the future. We
presently do not carry any key-man life insurance on any executive officers
within the Company.

We have very limited manufacturing operations and rely on outside sources of
supply for most of the strategic components used in our SET technology. Our
inability to obtain a sufficient supply of these components could significantly
impair our ability to serve our clients.

         We currently have very limited manufacturing capabilities and
experience in manufacturing the components used in our SET technology process,
and we intend to continue to rely on outside sources of supply for most of the
strategic components utilized in the SET technology. If we were unable to obtain
a sufficient supply of required components, we could experience significant
delays in the manufacture of the SET technology equipment, which could result in
the loss of orders and customers and could have a material adverse affect on our
business and market goodwill, which will materially reduce the value of your
investment. In addition, if the cost of raw materials or finished components
were to increase, we may not be able to pass the increase to our customers. The
use of outside suppliers also entails risks of quality control and disclosure of
proprietary information.

Certain members of our Board of Directors have a potential conflict of interest,
which may cause them to place the interests of another company before those of
our Company to the detriment of our business.

         Two out of seven members of our Board of Directors also serve as
directors of Commodore Separation Technologies, Inc. ("Commodore Separation").
These directors may have potential conflicts of interest with respect to, among
other things, potential corporate opportunities, business combinations, joint
ventures and/or other business opportunities that may become available to them.
Our business may be materially adversely affected if these directors choose to
place the interests of Commodore Separation before those of our Company and we
fail to resolve any of those conflicts in our favor.

Future sales of our common stock may have a depressive effect on the market
price of our stock.

         Sales of substantial amounts of our common stock, or the perception
that those sales could occur, could adversely affect prevailing market prices
for our common stock. On a fully-diluted basis (not including the shares of our
common stock underlying any of our outstanding convertible preferred stock),
approximately 87,137,343 shares of our common stock would be outstanding on the
date of this prospectus. Of such shares, 36,194,164 shares would be freely
tradable without restriction or further registration under the Securities Act of
1933, as amended (the "Securities Act") except to the extent those shares are
held by our "affiliates." The remaining 50,943,178 shares are "restricted
securities" as defined in Rule 144 promulgated under the Securities Act, and may
only be sold in the public market if those shares are registered under the

                                       8


Securities Act, or sold in accordance with Rule 144 or another exemption from
registration.

Conversion of our Series E and the Series F convertible preferred stock may
result in a significant number of additional shares of our common stock that may
be sold into the market, which could decrease the market price of our common
stock and materially adversely affect the value of your investment. Short sales
of our common stock could also result in a decline in the price of our common
stock.

         To the extent our 335,000 shares of Series E convertible preferred
stock and 266,700 shares of Series F convertible preferred stock are converted
into shares of our common stock, or dividends related to those securities are
paid in shares of our common stock rather than cash, a significant number of
additional shares of common stock may be sold into the market, which could
decrease the price of our common stock due to additional supply of shares
relative to demand in the market. In that case, we could be required to issue an
increasingly greater number of shares of our common stock upon future
conversions of Series E convertible preferred stock and Series F convertible
preferred stock, sales of which could further depress the price of our common
stock and have a material adverse effect on the value of your investment.
Moreover, since the conversion prices of the Series E convertible preferred
stock and Series F convertible preferred stock will be based on the average of
the closing prices of our common stock over a period of ten trading days prior
to conversion, the conversion prices could be less than the actual market price
of our common stock on the date of conversion.

         If the sale of a large amount of shares of our common stock upon
conversion of the Series E convertible preferred stock and the Series F
convertible preferred stock results in a decline in the price of our common
stock, this event could encourage short sales of our common stock by the selling
stockholders listed in this prospectus, as well as other stockholders, or margin
calls upon investors in our common stock. Short sales or margin calls could
place further downward pressure on the price of our common stock.

         Based on a conversion price of approximately $0.25 per share, the
outstanding shares of Series E convertible preferred stock and Series F
convertible preferred stock outstanding on March 15, 2001 would be convertible
into an aggregate of approximately 20,517,456 shares of our common stock,
representing approximately 28.68% of the common stock that would be outstanding
following the conversion, based upon the number of shares of our common stock
outstanding on March 15, 2001. As of March 15, 2001, 141,500 shares of Series E
convertible preferred stock and Series F convertible preferred stock have been
converted into shares of our common stock.

The market price of our common stock has fluctuated considerably and will
probably continue to do so.

         The stock markets have experienced extreme price and volume
fluctuations, and the market prices for our common stock and publicly traded
warrants have been historically volatile. The market prices of our securities
could be subject to wide fluctuations in the future as well in response to a
variety of events or factors, some of which may be beyond our control. These
could include, without limitation:

         o    future announcements of new competing technologies;

         o    changing policies and regulations of the federal government and
              state governments;

         o    the status of our patent protection and other intellectual
              property rights;

         o    quarterly fluctuations in our financial results;

         o    liquidity of the market for our securities;

         o    public perception of our Company and our entry into new markets;

         o    general conditions in our Company's industry and the economy; and

         o    other risk factors described in this prospectus.


                                       9


Our charter contains provisions related to authorized, unissued preferred stock
that may inhibit a change of control of our Company under circumstances that
could give you an opportunity to realize a premium over prevailing market prices
of our securities.

         Our certificate of incorporation and by-laws contain provisions that
could make it more difficult for a third party to acquire the Company under
circumstances that could give stockholders an opportunity to realize a premium
over then-prevailing market prices of our securities. Our certificate of
incorporation authorizes our Board of Directors to issue preferred stock without
stockholder approval and upon terms as it may determine. The rights of holders
of our common stock are subject to, and may be adversely affected by, the rights
of future holders of preferred stock. In addition, our by-laws require
stockholders to provide advance notice to nominate candidates for election as
directors and to submit proposals for consideration at stockholder meetings.
Section 203 of the Delaware General Corporation Law makes it more difficult for
an "interested stockholder" (generally a 15% stockholder) to effect various
business combinations with a corporation for a three-year period after the
stockholder becomes an "interested stockholder." In general, these provisions
may discourage a third party from attempting to acquire our Company and,
therefore, may inhibit a change of control of our Company.

Our business could still be disrupted by residual consequences of the Year 2000
problem.

         Prior to January 1, 2000, there was a great deal of concern regarding
the ability of computers to adequately recognize 21st century dates from 20th
century dates due to the two-digit date fields used by many systems. Computer
experts have warned that there may still be residual consequences of the change
in centuries and any such difficulties may, depending upon their pervasiveness
and severity, have a material adverse effect on our business, financial
condition and results of operations. Any of the following could have a material
adverse effect on our business operations:

         o    a failure to fully identify all Year 2000 dependencies in our
              systems;

         o    a failure to fully identify all Year 2000 dependencies in the
              systems of third parties with whom we do business including our
              collaborative partners, suppliers, and customers;

         o    a failure of any third party with whom we do business to
              adequately address their Year 2000 issues including our
              collaborative partners, suppliers, and customers;

         o    the failure of any contingency plans developed to protect our
              business and operations from Year 2000-related interruptions; and

              delays in the implementation of new systems resulting from Year
              2000 problems.

                           FORWARD-LOOKING STATEMENTS

         This prospectus includes "forward-looking statements" within the
meaning of Section 27A of the Securities Act of 1933, as amended, and Section
21E of the Securities Exchange Act of 1934, as amended (the "Exchange Act"),
based on our current expectations and projections about future events. These
forward-looking statements are subject to a number of risks and uncertainties
which could cause our actual results to differ materially from historical
results or those anticipated. Certain of those risks and uncertainties are
beyond our control. The words "believe," "expect," "anticipate" and similar
expressions identify forward-looking statements. We undertake no obligation to
publicly update or revise any forward-looking statements, whether as a result of
new information, future events or otherwise. New risk factors emerge from time
to time and it is not possible for us to predict all of them, nor can we assess
the impact of all of those risk factors on our business or the extent to which
any factor, or combination of factors, may cause actual results to differ
materially from those forecast in any forward-looking statements. Given these
risks and uncertainties, investors should not place undue reliance on
forward-looking statements as a prediction of actual results. Please see "Risk
Factors" for a discussion of the risks that are relevant to us at this time.


                                       10


                      ABOUT COMMODORE APPLIED TECHNOLOGIES

         We are an environmental solutions company providing a range of
engineering, technical, and financial services to the public and private sectors
related to:

         o    remediating contamination in soils, liquids and other materials
              and disposing of or reusing certain waste by-products by utilizing
              our proprietary SET technology;

         o    the settlement of complex, long-tail and latent insurance claims
              by utilizing our proprietary risk modeling process ("FOCUS"); and

         o    providing services related to, environmental management for
              on-site and off-site identification, investigation remediation and
              management of hazardous, mixed and radioactive waste.

         We believe that the SET technology is the only patented, non-thermal,
portable and scalable process that is currently available for treating and
decontaminating soils, liquids and other materials containing PCBs, pesticides,
dioxins, chemical weapons and warfare agents and other toxic contaminants.
Furthermore, we believe that the proprietary FOCUS program developed by DRM is
the only automated risk management system that fully incorporates all of the
variables necessary to determine liability and settlement targeting necessary
for DRM insurance recoveries.

         The Company's corporate mission is to serve the environmental
remediation market from two primary operating centers: (a) to profitably provide
government and industry with engineering and remediation solutions to long-tail
environmental problems, and (b) to profitably negotiate and settle long-tail
environmental claims domestically and internationally. Our strategy will focus
the Company on the unique and high profit niches of environmental claims
settlement and recovery, hazardous materials conversion and waste remediation.

         Demand for our environmental technology and financial services is
anticipated to arise principally from the following sources:

         o    the need for alternative environmental treatment and disposal
              methods for toxic substances (such as the SET technology), which
              involve limited safety risks with respect to air pollution and
              transportation of hazardous materials and do not result in large
              volumes of residual waste that require further treatment prior to
              disposal;

         o    the need to obtain available insurance recoveries in a negotiated
              manner (utilizing the FOCUS process) to compensate clients for a
              portion of their past, current and anticipated obligations, while
              minimizing the costs and time associated in a litigated recovery
              environment;

         o    stricter legislation and regulations mandating new or increased
              levels of air and water pollution control and solid waste
              management; and

         o    the need to provide appropriate risk management tools and
              mechanisms associated with present and future remediation risks on
              impaired properties and facilities.

         Our business strategy is to expand our environmental technology and
financial services businesses by:

         o    implementing the SET technology on selected niche markets within
              certain strategic environmental market segments, such as
              government mixed waste remediation and chemical weapons
              demilitarization, where we believe the SET technology offers the
              greatest value and meets pressing customer needs;

         o    focusing DRM's marketing efforts with aggressive joint working,
              alliances and marketing arrangements with established associations
              and representatives of Fortune 1000 companies worldwide;


                                       11


         o    developing strategic insurance brokerage arrangements and
              collaborations, through joint ventures or acquisitions, to further
              expand the business offerings and services of DRM to their
              existing and future clientele; and

         o    establishing additional collaborative joint working and marketing
              arrangements with established engineering and environmental
              service organizations to pursue commercial opportunities in the
              public and private sector.

We are incorporated under the laws of the State of Delaware. Our principal
executive offices are located at 2121 Jamieson Avenue, Suite 1406, Alexandria,
Virginia 22314, and our telephone number at that address is (703) 567-1284.





                               RECENT DEVELOPMENTS



$500,000 Brewer Promissory Note, Extension and Partial Conversion

         On September 15, 2000, we issued and sold to S. Brewer Enterprises,
Inc. (the "SB Enterprises") a 9.75% Secured Promissory Note (the "Brewer
Promissory Note") in the aggregate principal amount of $500,000. In connection
with the Notes, Commodore Environmental Services, Inc., pledged to the SB
Enterprises 500,000 shares of our common stock owned by Commodore Environmental
Services, Inc. at a purchase price of $.01 per share, as security for the Brewer
Promissory Note. The Company shall pay SB Brewer Enterprises the interest on a
monthly basis in arrears and pay the outstanding principal amount on the
earliest to occur (the "Maturity Date") of (i) the sale of the Company's
interest in the Teledyne-Commodore, LLC; or (iii) on March 15, 2001. The Brewer
Promissory Note may be prepaid at any time without penalty.

         On March 15, 2001, SB Enterprises executed an Amended and Restated
Promissory Note (the "Restated Brewer Note"), which extended the maturity date
of the note until December 31, 2001. Additionally, the conversion feature of the
Restated Brewer Note was changed to the 5-day average closing price of the
Company's common stock prior to a conversion notice. On April 9, 2001, SB
Enterprises issued a conversion notice for $250,000 of the outstanding principle
of the Brewer Restated Note.

$500,000 Bridge Loan and Extension

         On November 13, 2000, we issued and sold to certain investors (the
"Investors") 12% Senior Secured Promissory Notes (the "Bridge Loan Notes") in
the aggregate principal amount of $500,000. In connection with the Notes,
Commodore Environmental Services, Inc. issued and sold to the Investors
1,000,000 shares of our common stock owned by Commodore Environmental Services,
Inc, at a purchase price of $.01 per share. We shall pay each Investor the
outstanding principal amount, together with all accrued and unpaid interest on
the earliest to occur (the "Maturity Date") of (i) the prepayment of the Notes
out of one hundred percent (100%) of the first proceeds received by us as a cash
distribution (whether in the form of an intercompany dividend, bonus, loan or
otherwise) from DRM, or (ii) the consummation of a contemplated $2,000,000 debt
financing with BHC Funding, Inc. or (iii) on February 12, 2001. The Notes may be
prepaid at any time, on five-(5) business days prior notice, without penalty. We
did not pay the Notes as of the February 12, 2001 Maturity Date.

On April 16, 2001, the Investors executed a Memorandum of Understanding to
extend the payment date of the $500,000 of Bridge Loan Notes. Three of the
holders of the Bridge Loan Notes have granted payment extensions until June 30
and July 31, 2001, while the fourth holder of the Bridge Loan Notes has extended
only until May 1, 2001. If the fourth holder of the Bridge Loan Notes declares a


                                       12


default on May 1, 2001, the other three holders of the Bridge Loan Notes also
are permitted to declare a default. As of May 4, 2001 the Company has not been
notified of the holder's intent to declare a default on the Weiss Group Note. In
connection with the Bridge Loan Extension, the Company issued to the Investors
500,000 warrants for 500,000 shares of the Company's common stock at an exercise
price of $0.22 per share.



                                 USE OF PROCEEDS

         All of the shares of common stock offered through this prospectus are
being sold by or for the selling stockholders, and we will not receive any
proceeds from those sales. We will, however, receive the exercise price upon the
exercise of warrants held by William J. Russell, Tamie P. Speciale, Diane
Archangeli and Arthur Berry & Company, Inc. See the "Selling Stockholders"
section for a list of the respective exercise prices applicable to each of the
selling shareholders. We plan to use all proceeds we receive from the exercise
of those warrants for working capital and general corporate purposes.





                              SELLING STOCKHOLDERS

         The following table sets forth:

         o    the name of each selling stockholder;

         o    the number of shares of our common stock, and the percentage (if
              1% or more) of the outstanding shares of our common stock, owned
              as of March 15, 2001;

         o    the number of shares which may be sold through this prospectus for
              the account of the selling stockholder; and

         o    the number of shares of our common stock, and the percentage (if
              1% or more) of the outstanding shares of our common stock, that
              will be owned by the selling stockholder, assuming the selling
              stockholders sell all the shares offered through this prospectus.

The information included below is based upon information provided to us by the
selling stockholders. The selling stockholders purchased or otherwise acquired
the securities to be resold in the ordinary course of business. Because each
selling stockholder may offer all, some or none of the shares of common stock
the selling stockholder holds, the following table has been prepared on the
assumption that all of the shares offered through this prospectus will be sold
to parties unaffiliated with the selling stockholders. At the time of purchase
there were, and as of the date of this prospectus there are, no agreements,
arrangements or understandings, directly or indirectly, with any person to
distribute any of the securities to be resold. Except as indicated, none of the
selling stockholders has had a material relationship with us within the past
three years, other than as a result of ownership of shares of our common stock
or other securities. Unless otherwise indicated, the selling stockholders have
sole voting and investment power with respect to their respective shares.



                                       13



         The number of shares of our common stock indicated below that may be
resold through this prospectus by the persons listed below represents the number
of shares of common stock we agreed to register for resale pursuant to: (i) a
Registration Rights Agreement, dated as of August 30, 2000 in connection with
the acquisition of DRM; (ii) a Registration Rights Agreement dated as of
November 13, 2000 in connection with the $500,000 Bridge Loan Notes; (iii)
underlying warrants issued to holders of the Bridge Loan Extension for an
extension of the due date of the Bridge Loan Notes; and (iv) the Restated Brewer
Note and the subsequent partial conversion of the Brewer Promissory Note. The
shares issued or issuable in connection with our acquisition of 81% of DRM are
subject to a restriction in an Amended and Restated Stock Purchase Agreement
that restricts the sale of those shares prior to August 30, 2001.





                                                                         Number of
                                                                           Shares
                                          Shares of Common Stock     Which May be Sold      Shares of Common Stock
                                          Owned Prior to the Sale         Through            Owned After the Sale
                                                                      This Prospectus
                                        ---------------------------------------------------------------------------
    Name And Position/Relationship         Number        Percent           Number            Number         Percent
    ------------------------------         ------        -------           ------            ------         -------

                                                                                              
William J. Russell (1)                  7,600,000(2)     14.71%            7,300,000(3)          300,000       *
Tamie P. Speciale (4)                   7,600,000(5)     14.71%            7,300,000(3)          300,000       *
Shelby T. Brewer (6)                    1,985,167(7)      3.82%            1,141,667(8)          843,500     1.63%
Dispute Resolution Management, Inc.     1,580,000(9)      3.10%            1,580,000(3)                0       *
Mathers Associates                       600,000(10)      1.17%             600,000(11)                0       *
Klass Partners, Ltd.                     500,000(12)        *               500,000(11)                0       *
Diane Archangeli (13)                    345,000(14)        *                300,000(3)           45,000       *
Jon Paul Hannesson                       294,705(15)        *               150,000(11)          144,705       *
Krista S. Hannesson                      294,705(16)        *               150,000(11)          144,705       *
Stephen A. Weiss                         100,000(17)        *               100,000(11)                0       *
Claudio M. Guazzoni                       25,950(18)        *                25,950(19)                0       *
David M. McCarthy                         25,950(18)        *                25,950(19)                0       *
Arthur Berry & Company, Inc. (8)          20,000(20)        *                20,000(21)                0       *
Samuel Milbank                            17,300(18)        *                17,300(19)                0       *
Ari Bayme                                 12,000(18)        *                12,000(19)                0       *
Louis Szilezy                             10,000(18)        *                10,000(19)                0       *
Phyllis Reyes                              2,800(18)        *                 2,800(19)                0       *
Augusto Latorre                            2,000(18)        *                 2,000(19)                0       *
Philip Berliner                            2,000(18)        *                 2,000(19)                0       *
Vincent Trapasso                           2,000(18)        *                 2,000(19)                0       *



         *    Represents less than 1% of the outstanding shares of our common
              stock. Percentages based on 52,060,445 shares of our common stock
              outstanding on April 30, 2001.

         (1)  Mr. Russell has served as an executive officer of DRM, which is an
              81% owned subsidiary of the Company, since 1996.

         (2)  Consists of (i) 6,960,000 shares of our common stock issued to Mr.
              William J. Russell and Nancy E. Russell, with joint tenancy and
              rights of survivorship, by the Company in connection with our
              acquisition of 81% of DRM; (ii) 300,000 shares of our common stock
              underlying currently exercisable employee stock options granted to
              Mr. Russell at an exercise price of $1.125 per share; and (iii)
              340,000 shares of our common stock underlying a currently
              exercisable 5-year warrant at an exercise price of $2.00 per share
              granted to Mr. William J. Russell and Nancy E. Russell, with joint

                                       14


              tenancy and rights of survivorship, by the Company in connection
              with our acquisition of 81% of DRM. The calculation does not
              include 1,580,000 shares of the Company's common stock held by
              DRM, since these shares are held for future issuance to certain
              employees and other individuals other than Mr. Russell, in
              connection with our acquisition of 81.0% of DRM. The shares issued
              or issuable in connection with our acquisition of 81% of DRM are
              subject to a restriction in an Amended and Restated Stock Purchase
              Agreement that restricts the sale of those shares prior to August
              30, 2001.


         (3)  Pursuant to a Registration Rights Agreement, dated as of August
              30, 2000, by and among the Company and William J. Russell, Tamie
              P. Speciale and other persons who are party signatories (the
              "Holders"), we agreed to register an aggregate of 16,500,000
              shares of our common stock for sale by the Holders. The Holders
              may receive shares of our common stock upon the exercise of their
              warrants to purchase up to an aggregate of 1,000,000 shares of our
              common stock.

         (4)  Ms. Speciale has served as an executive officer of DRM since 1996.

         (5)  Consists of (i) 6,960,000 shares of our common stock issued to
              Tamie P. Speciale and George H. Speciale, with joint tenancy and
              rights of survivorship, by the Company in connection with our
              acquisition of 81% of DRM; (ii) 300,000 shares of our common stock
              underlying currently exercisable employee stock options granted to
              Ms. Speciale at an exercise price of $1.125 per share; and (iii)
              340,000 shares of our common stock underlying a currently
              exercisable 5-year warrant at an exercise price of $2.00 per share
              granted to Ms. Tamie P. Speciale and George H. Speciale, with
              joint tenancy and rights of survivorship, by the Company in
              connection with our acquisition of 81% of DRM. The calculation
              does not include 1,580,000 shares of the Company's common stock
              held by DRM, since these shares are held for future issuance to
              certain employees and other individuals other than Ms. Speciale,
              in connection with our acquisition of 81% of DRM. The shares
              issued or issuable in connection with our acquisition of 81% of
              DRM are subject to a restriction in an Amended and Restated Stock
              Purchase Agreement that restricts the sale of those shares prior
              to August 30, 2001.

         (6)  Mr. Brewer served as Chief Executive Officer and President of
              Commodore Solutions, Inc. ("Solutions"), and a director of the
              Company since April 2000. Mr. Brewer assumed the positions of
              Chairman, Chief Executive Officer and President of the Company as
              of January 15, 2001.

         (7)  Consists of: (i) 3,500 shares of our common stock; (ii) 840,000
              shares of our common stock underlying currently exercisable stock
              options granted to Mr. Brewer by the Company under the Plan; (iii)
              100,000 shares of our common stock underlying a currently
              exercisable 2-year warrant at an exercise price of $1.06 per share
              granted to SB Enterprises by the Company in connection with the
              Brewer Promissory Note; and (iv) 1,041,667 shares of our common
              stock issued pursuant to the Restated Brewer Note, dated as of
              March 15, 2001, between the Company and SB Enterprises and a
              subsequent conversion notice for 50% of the outstanding principal
              dated as of April 9, 2001.


         (8)  Pursuant to a Registration Rights Agreement, dated as of September
              15, 2000, between the Company and SB Enterprises, we agreed to
              register (i) 100,000 shares of our common stock underlying a
              currently exercisable 2-year warrant at an exercise price of $1.06
              per share granted to SB Enterprises by the Company in connection
              with the Brewer Promissory Note; and (ii) 1,041,667 shares of our
              common stock issued pursuant to the Restated Brewer Note, dated as
              of March 15, 2001, between the Company and SB Enterprises and a
              subsequent conversion notice for 50% of the outstanding principal
              dated as of April 9, 2001.

         (9)  Consists of (i) 1,580,000 shares of our common stock issued to
              DRM, by the Company in connection with our acquisition of 81% of
              DRM. These shares of the Company's common stock will be
              distributed to certain employees of DRM and individuals in
              connection with the acquisition of 81% of DRM on August 30, 2001.
              These shares of the Company's common stock will not be distributed
              to Mr. Russell or Ms. Speciale. The shares issued or issuable in
              connection with our acquisition of 81% of DRM are subject to a
              restriction in an Amended and Restated Stock Purchase Agreement
              that restricts the sale of those shares prior to August 30, 2001.

                                       15


         (10) Consists of (i) 300,000 shares of our common stock issued pursuant
              to a Securities Purchase Agreement, dated as of November 13, 2000,
              by and among Commodore Environmental Services, Inc., the Company,
              and Mathers Associates in connection with the Bridge Loan Notes;
              and (ii) 300,000 shares of our common stock underlying a currently
              exercisable 2-year warrant at an exercise price of $0.22 per share
              granted to Mathers Associates by the Company in connection with
              the Bridge Loan Extension.


         (11) Pursuant to a Registration Rights Agreement, dated as of November
              13, 2000, by and among our Company and Mathers Associates, Klass
              Partners, Ltd., Jon Paul Hannesson and Stephen A. Weiss (the
              "Investors"), we agreed to register an aggregate of 1,000,000
              shares of our common stock for sale by the Investors in connection
              with the Bridge Loan Notes. Additionally, the Company agreed to
              register 500,000 shares of common stock underlying currently
              exercisable warrants at an exercise price of $0.22 per share
              granted to Mathers Associates, Jon Paul Hannesson and Stephen A.
              Weiss in connection with the Bridge Loan Extension.

         (12) Consists of 500,000 shares of our common stock issued pursuant to
              a Securities Purchase Agreement, dated as of November 13, 2000, by
              and among Commodore Environmental Services, Inc., the Company, and
              Klass Partners, Ltd in connection with the Bridge Loan Notes.

         (13) Ms. Archangeli has served as a Vice President of DRM since 1997.

         (14) Consists of (i) 45,000 shares of our common stock underlying
              currently exercisable employee stock options granted to Ms.
              Archangeli at an exercise price of $1.125 per share; and (ii)
              300,000 shares of our common stock underlying a currently
              exercisable 5-year warrant at an exercise price of $2.00 per share
              granted to Ms. Archangeli by the Company in connection with our
              acquisition of 81% of DRM. The shares issued or issuable in
              connection with our acquisition of 81% of DRM are subject to a
              restriction in an Amended and Restated Stock Purchase Agreement
              that restricts the sale of those shares prior to August 30, 2001.

         (15) Consists of (i) 40,000 shares of our common stock; (ii) 75,000
              shares of our common stock issued pursuant to a Securities
              Purchase Agreement, dated as of November 13, 2000, by and among
              Commodore Environmental Services, Inc., the Company, and Jon Paul
              Hannesson in connection with the Bridge Loan Notes; (iii) 75,000
              shares of our common stock underlying a currently exercisable
              5-year warrant at an exercise price of $0.22 per share granted to
              Jon Paul Hannesson by the Company in connection with the Bridge
              Loan Extension; and (iv) Mr. Hannesson's indirect beneficial
              ownership of our common stock based upon his ownership of
              1,000,000 shares of common stock of Commodore Environmental
              Services, Inc.

         (16) Consists of (i) 40,000 shares of our common stock; (ii) 75,000
              shares of our common stock issued pursuant to a Securities
              Purchase Agreement, dated as of November 13, 2000, by and among
              Commodore Environmental Services, Inc., the Company, and Krista S.
              Hannesson in connection with the Bridge Loan Notes; (iii) 75,000
              shares of our common stock underlying a currently exercisable
              5-year warrant at an exercise price of $0.22 per share granted to
              Krista S. Hannesson by the Company in connection with the Bridge
              Loan Extension; and (iv) Ms. Hannesson's indirect beneficial
              ownership of our common stock based upon her ownership of
              1,000,000 shares of common stock of Commodore Environmental
              Services, Inc.

         (17) Consists of (i) 50,000 shares of our common stock issued pursuant
              to a Securities Purchase Agreement, dated as of November 13, 2000,
              by and among Commodore Environmental Services, Inc., the Company,
              and Stephen A. Weiss in connection with the Bridge Loan Notes; and
              (ii) 50,000 shares of our common stock underlying a currently
              exercisable two year warrant at an exercise price of $0.22 per
              share granted to Stephen A. Weiss by the Company in connection
              with the Bridge Loan Extension. Mr. Weiss is a shareholder of
              Greenberg Traurig LLP, legal counsel to DRM and Messrs. Russell
              and Speciale, and our former securities counsel.


                                       16


         (18) Consists of shares of our common stock issued pursuant to a
              Settlement Agreement, dated as of April 4, 2000, by and among the
              Company and The Zanett Securities Corporation.

         (19) Consists of shares of our common stock issued pursuant to a
              Settlement Agreement, dated as of April 4, 2000, by and among the
              Company and The Zanett Securities Corporation, in which the
              Company agreed to register an aggregate of 75,000 shares of our
              common stock for sale by the listed employees of Zanett Securities
              Corporation.

         (20) Arthur Berry and Company Inc. has served as business brokers and
              consultants to DRM since 1998.

         (21) Consists of 20,000 shares of our common stock underlying a
              currently exercisable 5-year warrant at an exercise price of $2.00
              per share granted to Arthur Berry & Company, Inc. by the Company
              in connection with our acquisition of DRM.



                              PLAN OF DISTRIBUTION

         All or a portion of the shares offered hereby may be sold, from time to
time, by or for the selling stockholders in one or more transactions on the
American Stock Exchange, in the public market off the American Stock Exchange,
in privately negotiated transactions, or in a combination of such transactions.
Such sales may be made either at fixed prices which may be changed, at market
prices prevailing at the time of sale, at prices related to prevailing market
prices or at negotiated prices.


         The shares issued or issuable in connection with our acquisition of 81%
of DRM are subject to a restriction in an Amended and Restated Stock Purchase
Agreement that restricts the sale of those shares prior to August 30, 2001. The
shares may be sold by or for the selling stockholders by one or more of the
following methods, without limitation:

         o    block trades in which a broker or dealer will attempt to sell the
              shares as agent, but may position and resell a portion of the
              block as principal to facilitate the transaction;

         o    purchases by a broker or dealer as principal and resale by such
              broker or dealer for its account pursuant to this prospectus;

         o    an exchange distribution in accordance with the rules of such
              exchange;

         o    ordinary brokerage transactions and transactions in which a broker
              may solicit purchasers;

         o    privately negotiated transactions;

         o    short sales; and

         o    a combination of any such methods of sale.

         In effecting sales, brokers and dealers engaged by the selling
stockholders may arrange for other brokers or dealers to participate. Brokers or
dealers may receive compensation in the form of discounts, concessions or
commissions from the selling stockholders (or, if any such broker-dealer acts as
agent for the purchaser of such shares, from such purchaser) in amounts to be
negotiated which may be less than, or in excess of, those customary in the types
of transactions involved. Any shares of common stock that qualify for sale
pursuant to Rule 144 under the Securities Act may be sold under Rule 144 rather
than pursuant to this prospectus.

         The selling stockholders and any broker-dealers or agents that
participate with the selling stockholders in the distribution of the shares may
be deemed to be "underwriters" within the meaning of the Securities Act, and any
commissions received by them and any profit received by them may be deemed to be
underwriting commissions or discounts under the Securities Act.


                                       17


         Under the applicable rules and regulations of the Exchange Act, any
person engaged in the distribution of the shares may not simultaneously engage
in market-making activities with respect to our common stock for a period of one
business day prior to the commencement of such distribution. In addition and
without limiting the foregoing, each selling stockholder will be subject to
applicable provisions of the Exchange Act and the rules and regulations
hereunder, including, without limitation, Regulation M, provisions of which may
limit the timing of purchases and sales of our common stock by the selling
stockholders. All of the foregoing may limit the marketability of the shares.

         To the Company's knowledge, no underwriting arrangements have been
entered into by the selling stockholders with respect to the shares as of the
date of this prospectus. If we are notified by a selling stockholder that any
material arrangement has been entered into with a broker or dealer for the sale
of shares through a block trade, special offering or secondary distribution, or
a purchase by a broker or dealer, we will file a supplement to this prospectus,
if required, pursuant to Rule 424(b) under the Securities Act, disclosing

         o    the name of each such selling stockholder and of the participating
              broker or dealer;

         o    the number of shares involved;

         o    the price at which such shares were sold;

         o    the commissions paid or the discounts or concessions allowed to
              such broker or dealer, where applicable

         o    that such broker or dealer did not conduct any investigation to
              verify the information set out or incorporated by reference in
              this prospectus; and

         o    other facts material to the transaction.

         We will maintain the effectiveness of the registration statement of
which this prospectus is a part until the earlier of (i) two years after the
effective date of the registration statement, or (ii) such time as all the
shares registered hereby have been sold or are no longer subject to volume or
manner of sale restrictions under the Securities Act.

         In order to comply with the securities laws of certain states, if
applicable, the shares will be sold in such jurisdictions only through
registered or licensed brokers or dealers.

We will pay all expenses incurred to register the shares, which are estimated to
be approximately $42,558, but individual selling stockholders will pay all
brokerage commissions and other expenses incurred by them. There is no assurance
that any of the selling stockholders will sell any or all of the shares offered
hereby.

                                  LEGAL MATTERS

         The validity of the shares offered hereby has been passed upon by our
counsel, McGuireWoods, LLP, Jacksonville, Florida.

                                     EXPERTS

         The financial  statements of Commodore Applied  Technologies,  Inc. and
Subsidiaries  for the years ended  December 31,  2000 and 1999,  incorporated in
this  Prospectus by reference to the Company's  Annual Report on form 10-K/A for
the years  ended  December 31,  2000 and  1999,  have  been so  incorporated  in
reliance on the report (which contains an explanatory  paragraph relating to the
Company's  ability to continue as a going  concern as described in Note 2 to the
financial  statements) of Tanner + Co.,  independent  accountants,  given on the
authority of said firm as experts in auditing and accounting.

         The financial  statements of Commodore Applied  Technologies,  Inc. and
Subsidiaries  for  the  year  ended  December 31,  1998,  incorporated  in  this
Prospectus  by reference to the  Company's  Annual Report on Form 10-K/A for the
year ended  December 31,  2000,  have been so  incorporated  in  reliance on the

                                       18

report  (which  contains an  explanatory  paragraph  relating  to the  Company's
ability to continue as a going  concern as described in Note 2 to the  financial
statements) of PricewaterhouseCoopers LLP, independent accountants, given on the
authority of said firm as experts in auditing and accounting.

         The financial statements of Dispute Resolution Management, Inc. for the
year ended  December 31,  1999,  incorporated in this Prospectus by reference to
the Company's Annual Report on Form 10-K/A for the year ended December 31, 2000,
have been so incorporated in reliance on the report of Foote, Passey,  Griffin &
Co,  L.C.,  independent  accountants,  given on the  authority  of said  firm as
experts in auditing and accounting.



                       WHERE YOU CAN FIND MORE INFORMATION

         We file annual, quarterly and current reports, proxy statements and
other information with the Securities and Exchange Commission (the "SEC") that
are required to be filed under the Securities Exchange Act of 1934, as amended
(the "Exchange Act"). You may read and copy such reports, proxy statements and
other information at the SEC's public reference rooms located at 450 Fifth
Street, N.W., Washington, D.C. 20549, at Seven World Trade Center, Suite 1300,
New York, New York 10048, and at Northwest Atrium Center, 500 West Madison
Street, Suite 1400, Chicago, Illinois 60661-2511. Please call the SEC at
1-800-SEC-0330 for further information on the public reference rooms. Our SEC
filings are also available to the public from the SEC's internet site on the
World Wide Web at http://www.sec.gov. Copies of these reports, proxy statements
and other information also can be inspected at the offices of the American Stock
Exchange, 86 Trinity Place, New York, New York 10006.

         We have filed a registration statement on Form S-3 with the SEC with
respect to the shares. This prospectus constitutes a part of that registration
statement. As allowed by SEC rules, this prospectus does not contain all of the
information you can find in the registration statement and its exhibits. In
addition, there may have been changes in the facts set forth in this prospectus
since the date it was filed. For further information about us and our common
stock, you should consult the registration statement and its exhibits.
Statements in this prospectus regarding the contents of any documents are not
necessarily complete, and each statement is qualified in its entirety by
reference to the copy of the document on file with the SEC. You may inspect and
obtain copies of the registration statement and any of its amendments, including
exhibits filed as a part of the registration statement or an amendment to the
registration statement, through the entities listed above.

         The SEC allows us to "incorporate by reference" certain information we
file with the SEC, which means that we can disclose important information to you
by referring you to another document filed separately with the SEC. Information
contained in a previously filed document that we incorporate by reference is
considered to be a part of this prospectus, except for any information
superseded by information in this prospectus. Information that we file with the
SEC after the date of this prospectus will automatically update and supersede
the information contained or incorporated by reference in this prospectus.

         The following documents we filed or we may file with the SEC pursuant
to the Exchange Act (File No. 1-11871) are incorporated by reference into this
prospectus:

         (a)  our Annual Report on Form 10-K/A for the year ended December 31,
              2000 filed with the SEC on May 4, 2001;

         (b)  our Quarterly Reports on Form 10-Q for the fiscal quarters ended
              March 31, June 30, and September 30, 2000;

         (c)  our Current Reports on Form 8-K dated May 17, 2000 and August 30,
              2000;

         (d)  the description of our common stock contained in our registration
              statement on Form 8-A, dated June 24, 1996, as amended by our
              registration statement on Form 8-A/A, dated June 26, 1996, filed
              under Section 12(b) of the Exchange Act, including any amendment
              or report filed for the purpose of updating such information; and


                                       19


         (e)  all documents subsequently filed by the Company pursuant to
              Section 13(a), 13(c), 14 or 15(d) of the Exchange Act prior to the
              termination of the offering.


         We will provide without charge to each person, including any beneficial
owner, to whom a copy of this prospectus is delivered a copy of any or all
documents incorporated by reference into this prospectus except the exhibits to
such documents (unless such exhibits are specifically incorporated by reference
in such documents). Requests for copies can be made by writing or telephoning us
at our principal executive office at 2121 Jamieson Avenue, Suite 1406,
Alexandria, Virginia 22314, Attention: Secretary; telephone number (703)
567-1284.



                                       20






================================================================================



                                19,241,667 Shares


                      COMMODORE APPLIED TECHNOLOGIES, INC.


                                  Common Stock

                                  -------------

                                   PROSPECTUS

                                  -------------

                                  -------------

                                  May 04, 2001

                                  -------------

We have not authorized any dealer, salesperson or other person to give any
information or represent anything not contained or incorporated by reference in
this prospectus. You must not rely on any unauthorized information. This
prospectus does not offer to sell any shares in any jurisdiction where it is
unlawful. The information in this prospectus is current only as of its date.


================================================================================




                                       21


                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 14. Other expenses of issuance and distribution.

         The following table sets forth the costs and expenses in connection
with the sale and distribution of the securities being registered, other than
underwriting discounts and commissions. The selling stockholders will not pay
any of the listed expenses. All of the amounts shown are estimates, except the
Securities and Exchange Commission registration fee and American Stock Exchange
additional listing fee.

                                                                    To be Paid
                                                                      by the
                                                                    Registrant
SEC registration fee..............................................  $ 1058.00
Accounting fees and expenses......................................   5,000.00
Legal fees and expenses...........................................  10,000.00
American Stock Exchange additional listing fee....................  17,500.00
Printing and engraving costs......................................   7,000.00
Miscellaneous expenses............................................   2,000.00
                                                                    ----------
         Total....................................................  $42,558.00
                                                                    ==========



Item 15. Indemnification of Directors and Officers.

         Section 145(a) of the General Corporation Law of the State of Delaware
(the "General Corporation Law") provides that a Delaware corporation may
indemnify any person who was or is a party or is threatened to be made a party
to any threatened, pending or completed action, suit or proceeding, whether
civil, criminal, administrative or investigative (other than an action by or in
the right of the corporation) by reason of the fact that he or she is or was a
director, officer, employee or agent of the corporation or is or was serving at
the request of the corporation as a director, officer, employee or agent of
another corporation or enterprise, against expenses, judgments, fines and
amounts paid in settlement actually and reasonably incurred by him or her in
connection with such action, suit or proceeding if he or she acted in good faith
and in a manner he or she reasonably believed to be in or not opposed to the
best interests of the corporation, and, with respect to any criminal action or
proceeding, had no cause to believe his or her conduct was unlawful.

         Section 145(b) of the General Corporation Law provides that a Delaware
corporation may indemnify any person who was or is a party or is threatened to
be made a party to any threatened, pending or completed action or suit by or in
the right of the corporation to procure a judgment in its favor by reason of the
fact that such person acted in any of the capacities set forth above, against
expenses actually and reasonably incurred by him or her in connection with the
defense or settlement of such action or suit if he or she acted under similar
standards as set forth above, except that no indemnification may be made in
respect of any claim, issue or matter as to which such person shall have been
adjudged to be liable to the corporation unless and only to the extent that the
court in which such action or suit was brought shall determine that despite the
adjudication of liability, but in view of all the circumstances of the case,
such person is fairly and reasonably entitled to be indemnified for such
expenses which the court shall deem proper.

         Section 145 of the General Corporation Law further provides that to the
extent a director or officer of a corporation has been successful on the merits
or otherwise in the defense of any action, suit or proceeding referred to in
subsections (a) and (b) or in the defense of any claim, issue or matter therein,
he or she shall be indemnified against expenses actually and reasonably incurred
by him or her in connection therewith; that indemnification provided for by
Section 145 shall not be deemed exclusive of any other rights to which the
indemnified party may be entitled; and that the corporation may purchase and
maintain insurance on behalf of such person against any liability asserted
against him or her or incurred by him or her in any such capacity or arising out

                                       22


of his or her status as such, whether or not the corporation would have the
power to indemnify him or her against such liabilities under such Section 145.

         Section 102(b)(7) of the General Corporation Law provides that a
corporation in its original certificate of incorporation or an amendment thereto
validly approved by stockholders may eliminate or limit personal liability of
members of its board of directors or governing body for monetary damages for
breach of a director's fiduciary duty. However, no such provision may eliminate
or limit the liability of a director for breaching his or her duty of loyalty,
failing to act in good faith, engaging in intentional misconduct or knowingly
violating a law, paying a dividend or approving a stock repurchase or redemption
which was illegal, or obtaining an improper personal benefit. A provision of
this type has no effect on the availability of equitable remedies, such as
injunction or rescission, for breach of fiduciary duty. The Company's
Certificate of Incorporation contains such a provision.

         Article Thirteen of the Company's Certificate of Incorporation
eliminates the personal liability of directors and/or officers to the Company or
its stockholders for monetary damages for breach of fiduciary duty as a
director; provided that such elimination of the personal liability of a director
and/or officer of the Company does not apply to (i) any breach of such person's
duty of loyalty to the Company or its stockholders, (ii) acts or omissions not
in good faith or which involve intentional misconduct or a knowing violation of
law, (iii) actions prohibited under Section 174 of the General Corporation Law
(i.e., liabilities imposed upon directors who vote for or assent to the unlawful
payment of dividends, unlawful repurchases or redemption of stock, unlawful
distribution of assets of the Company to the stockholders without the prior
payment or discharge of the Company's debts or obligations, or unlawful making
or guaranteeing of loans to directors and/or officers), or (iv) any transaction
from which the director derived an improper personal benefit. In addition,
Article Fourteen of the Company's Certificate of Incorporation and Article VI of
the Company's By-Laws provide that the Company shall indemnify its corporate
personnel, directors and officers to the fullest extent permitted by the General
Corporation Law, as amended from time to time.

         The Company has in force a combined insurance policy with its
affiliates under which its directors and officers are insured (with limits of
$10 million per occurrence and $10 million in the aggregate) against certain
expenses in connection with the defense of such actions, suits or proceedings to
which they are parties by reason of being or having been directors or officers
of the Company.

         The Company and its officers, directors and other persons are entitled
to be indemnified under certain circumstances for certain securities law
violations in accordance with the provisions of an underwriting agreement dated
June 28, 1996, by and among the Company, Bentley J. Blum and National Securities
Corporation, as representative of the several underwriters.

         Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers or persons controlling the Company
as disclosed above, the Company has been informed that in the opinion of the
SEC, such indemnification is against public policy as expressed in the
Securities Act and is therefore unenforceable.

Item 16. Exhibits.

Exhibit                           Description
Number                            -----------
-------

*10.39            Warrant to purchase 340,000 shares of Common Stock of the
                  Company issued to William J. Russell. (3)
*10.40            Warrant to purchase 340,000 shares of Common Stock of the
                  Company issued to Tamie P. Speciale. (3)
*10.41            Warrant to purchase 300,000 shares of Common Stock of the
                  Company issued to Diane Archangeli. (3)
*10.42            Warrant to purchase 20,000 shares of Common Stock of the
                  Company issued to Arthur Berry & Company, Inc. (3)
*10.43            Specimen Form of Common Stock Certificate. (1)
*10.44            Promissory Note, dated September 15, 2000, issued to Shelby T.
                  Brewer in the principal amount of $500,000. (3)


                                       23



*10.45            Registration Rights Agreement, dated September 15, 2000,
                  issued to Shelby T. Brewer. (3)
*10.46            Stock Pledge Agreement, dated September 15, 2000, between
                  Commodore Environmental Technologies, Inc., and Shelby T.
                  Brewer. (3)
*10.47            Warrant to purchase 100,000 shares of Common Stock of the
                  Company issued to Shelby T. Brewer. (3)
*10.48            Amended and Restated Promissory Note, dated September 15,
                  2000, issued to Shelby T. Brewer in the principal amount of
                  $500,000. (3)
*10.49            Registration Rights Agreement, dated March 15, 2001, issued to
                  Shelby T. Brewer. (3)
*10.50            Secured Promissory Note, dated November 13, 2000, issued to
                  Klass Partners Ltd. in the principal amount of $250,000. (3)
*10.51            Secured Promissory Note, dated November 13, 2000, issued to
                  Mathers Associates in the principal amount of $150,000. (3)
*10.52            Secured Promissory Note, dated November 13, 2000, issued to
                  Jon Paul Hannesson in the principal amount of $75,000. (3)
*10.53            Secured Promissory Note, dated November 13, 2000, issued to
                  Stephen A. Weiss in the principal amount of $25,000. (3)
*10.54            Amended and Restated Stock Purchase Agreement, dated August
                  30, 2000, by and among the Company, Dispute Resolution
                  Management, Inc., William J. Russell and Tamie P. Speciale.
                  (2)
*10.55            Securities Purchase Agreement, dated November 13, 2000, by and
                  among the Company, Commodore Environmental Services, Inc.,
                  Mathers Associates, Klass Partners, Ltd., Jon Paul Hannesson
                  and Stephen A. Weiss. (3)
*10.56            Security Agreement, dated November 13, 2000, by and among
                  Mathers Associates, Klass Partners, Ltd., Jon Paul Hannesson,
                  Stephen A. Weiss and the Company. (3)
*10.57            Registration Rights Agreement, dated November 13, 2000, among
                  Mathers Associates, Klass Partners, Ltd., Jon Paul Hannesson,
                  Stephen A. Weiss and the Company. (3)
*10.58            Dispute Resolution Management, Inc. Undertaking Letter, dated
                  November 13, 2000. (3)
*10.70            Conversion Notice, dated April 9, 2001 between S. Brewer
                  Enterprises, Inc. and the Company for the conversion of
                  $250,000 of the Restated Brewer Note. (3)
*10.71            Memorandum of Understanding for Amendment of $500,000 CXI
                  Bridge Loan Documents, dated April 16, 2001, by and among the
                  Company, Commodore Environmental Services, Inc., Mathers
                  Associates, Jon Paul Hannesson and Stephen A. Weiss. (3)
*10.72            Klass Partners Ltd. Agreement for Amendment of CXI Bridge Loan
                  Documents, dated April 16, 2001, by the Company and Klass
                  Partners, Ltd. (3)
*10.73            Warrant to purchase 300,000 shares of Common Stock of the
                  Company issued to Mathers Associates. (3)
*10.74            Warrant to purchase 75,000 shares of Common Stock of the
                  Company issued to Jon Paul Hannesson. (3)
*10.75            Warrant to purchase 75,000 shares of Common Stock of the
                  Company issued to Krista S. Hannesson. (3)
*10.76            Warrant to purchase 50,000 shares of Common Stock of the
                  Company issued to Stephen A. Weiss. (3)
**5.1             Opinion of McGuireWoods, LLP.
**23.1            Consent of PricewaterhouseCoopers LLP.
*23.2             Consent of McGuireWoods, LLP (contained in Exhibit 5.1).
**23.3            Consent of Tanner & Co.
**23.4            Consent of Foote, Passey, Griffen & Co., LC

*  Previously filed electronically.

** Filed herewith electronically.

         1.   Incorporated herein by reference. Filed as an exhibit to the
              Company's Registration Statement on Form S-1 (Registration No.
              333-4396) filed with the Commission on May 2, 1996.

         2.   Incorporated herein by reference. Filed as an exhibit to the
              Company's Current Report on Form 8-K filed with the Commission on
              September 12, 2000.

         3.   Incorporated herein by reference. Filed as an exhibit to the
              Company's Annual Report on Form 10K/A (File No. 1-11871) filed
              with the Commission on May 04, 2001.

                                       24




Item 17. Undertakings.

         (a)      The undersigned registrant hereby undertakes:

                  (1) To file, during any period in which offers or sales are
         being made, a post-effective amendment to this registration statement:

                  (i)      To include any prospectus required by Section 10(a)
         (3) of the Securities Act of 1933;

                  (ii) To reflect in the prospectus any facts or events arising
         after the effective date of the registration statement (or the most
         recent post-effective amendment thereof) which, individually or in the
         aggregate, represent a fundamental change in the information set forth
         in the registration statement. Notwithstanding the foregoing, any
         increase or decrease in volume of securities offered (if the total
         dollar value of securities offered would not exceed that which was
         registered) and any deviation from the low or high end of the estimated
         maximum offering range may be reflected in the form of prospectus filed
         with the Commission pursuant to Rule 424(b) if, in the aggregate, the
         changes in volume and price represent no more than a 20 percent change
         in the maximum aggregate offering price set forth in the "Calculation
         of Registration Fee" table in the effective registration statement;

                  (iii) To include any material information with respect to the
         plan of distribution not previously disclosed in the registration
         statement or any material change to such information in the
         registration statement;

         provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not
         apply if the information required to be included in a post-effective
         amendment by those paragraphs is contained in periodic reports filed by
         the Company with the Commission pursuant to Section 13 or Section 15(d)
         of the Exchange Act that are incorporated by reference in the
         registration statement.

                  (2) That, for the purpose of determining any liability under
         the Securities Act, each such post-effective amendment shall be deemed
         to be a new registration statement relating to the securities offered
         therein, and the offering of such securities at that time shall be
         deemed to be the initial bona fide offering thereof.

                  (3) To remove from registration by means of a post-effective
         amendment any of the securities being registered which remain unsold at
         the termination of the offering.

         (b) The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act of 1933, each filing of the
registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Securities and Exchange Act of 1934 (and, where applicable, each filing of an
employee benefit plan's annual report pursuant to Section 15(d) of the
Securities and Exchange Act of 1934) that is incorporated by reference in the
registration statement shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.

         (c) Insofar as indemnification for liabilities arising under the
Securities Act of 1933 may be permitted to directors, officers and controlling
persons of the registrant pursuant to the foregoing provisions, or otherwise,
the registrant has been advised that in the opinion of the Securities and
Exchange Commission such indemnification is against public policy as expressed
in the Act and is, therefore, unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, the registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit to a court of appropriate jurisdiction the question whether such
indemnification by it is against public policy as expressed in the Act and will
be governed by the final adjudication of such issue.


                                       25



                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, as amended,
the registrant certifies that it has reasonable grounds to believe that it meets
all of the requirements for filing on Form S-3 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in the City of Alexandria, State of Virginia, on this 4th day
of May, 2001.

                                        COMMODORE APPLIED TECHNOLOGIES, INC.
                                        By:     /s/ SHELBY T. BREWER
                                                -------------------
                                                Shelby T. Brewer
                                                Chairman of the Board, President
                                                and Chief Executive Officer



                                POWER OF ATTORNEY

         KNOW ALL MEN BY THESE PRESENTS, that each person whose signature
appears below constitutes and appoints Shelby T. Brewer and James M. DeAngelis,
and each of them, his true and lawful attorneys-in-fact and agents, with full
power of substitution and re-substitution, for him and in his name, place and
stead, in any and all capacities, to sign any and all amendments (including
post-effective amendments) to this Registration Statement, and to file the same,
with all exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, and any other regulatory authority, granting
unto said attorneys-in-fact and agents, and each of them, full power and
authority to do and perform each and every act and thing requisite and necessary
to be done in and about the premises, as fully to all intents and purposes as he
might or could do in person, hereby ratifying and confirming all that said
attorneys-in-fact and agents or any of them, or their substitutes, may lawfully
do or cause to be done by virtue hereof.
                                -----------------

         Pursuant to the requirements of the Securities Act of 1933, as amended,
this Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.




               Signature                               Capacity                                 Date
               ---------                               --------                                 ----
                                                                                      

         /s/ SHELBY T. BREWER            Chairman of the Board, President and               May 04, 2001
         ---------------------           Chief Executive Officer (principal
           Shelby T. Brewer              executive officer)

        /s/ JAMES M. DEANGELIS           Senior Vice President and Chief                    May 04, 2001
        -----------------------          Financial Officer (principal
          James M. DeAngelis             financial and accounting officer)

         /s/ BENTLEY J. BLUM             Director                                           May 04, 2001
         --------------------
            Bentley J. Blum

         s/ HERBERT A. COHEN             Director                                           May 04, 2001
         --------------------
           Herbert A. Cohen

        /s/ PAUL E. HANNESSON            Director                                           May 04, 2001
        ----------------------
           Paul E. Hannesson



                                       26



                                                                                      

        /s/ DAVID L. MITCHELL            Director                                           May 04, 2001
        ----------------------
           David L. Mitchell

         /s/ EDWARD L. PALMER            Director                                           May 04, 2001
         ---------------------
           Edward L. Palmer

        /s/ WILLIAM R. TOLLER            Director                                           May 04, 2001
        ----------------------
           William R. Toller





                                       27


                                  EXHIBIT INDEX



  Exhibit                               Description
  Number                               -----------
  ------

*10.39        Warrant to purchase 340,000 shares of Common Stock of the Company
              issued to William J. Russell. (3)
*10.40        Warrant to purchase 340,000 shares of Common Stock of the Company
              issued to Tamie P. Speciale. (3)
*10.41        Warrant to purchase 300,000 shares of Common Stock of the Company
              issued to Diane Archangeli. (3)
*10.42        Warrant to purchase 20,000 shares of Common Stock of the Company
              issued to Arthur Berry & Company, Inc. (3)
*10.43        Specimen Form of Common Stock Certificate. (1)
*10.44        Promissory Note, dated September 15, 2000, issued to Shelby T.
              Brewer in the principal amount of $500,000. (3)
*10.45        Registration Rights Agreement, dated September 15, 2000, issued to
              Shelby T. Brewer. (3)
*10.46        Stock Pledge Agreement, dated September 15, 2000, between
              Commodore Environmental Technologies, Inc., and Shelby T. Brewer.
              (3)
*10.47        Warrant to purchase 100,000 shares of Common Stock of the Company
              issued to Shelby T. Brewer. (3)
*10.48        Amended and Restated Promissory Note, dated September 15, 2000,
              issued to Shelby T. Brewer in the principal amount of $500,000.
              (3)
*10.49        Registration Rights Agreement, dated March 15, 2001 issued to
              Shelby T. Brewer. (3)
*10.50        Secured Promissory Note, dated November 13, 2000, issued to Klass
              Partners Ltd. in the principal amount of $250,000. (3)
*10.51        Secured Promissory Note, dated November 13, 2000, issued to
              Mathers Associates in the principal amount of $150,000. (3)
*10.52        Secured Promissory Note, dated November 13, 2000, issued to Jon
              Paul Hannesson in the principal amount of $75,000. (3)
*10.53        Secured Promissory Note, dated November 13, 2000, issued to
              Stephen A. Weiss in the principal amount of $25,000. (3)
*10.54        Amended and Restated Stock Purchase Agreement, dated August 30,
              2000, by and among the Company, Dispute Resolution Management,
              Inc., William J. Russell and Tamie P. Speciale. (2)
*10.55        Securities Purchase Agreement, dated November 13, 2000, by and
              among the Company, Commodore Environmental Services, Inc., Mathers
              Associates, Klass Partners, Ltd., Jon Paul Hannesson and Stephen
              A. Weiss. (3)
*10.56        Security Agreement, dated November 13, 2000, by and among Mathers
              Associates, Klass Partners, Ltd., Jon Paul Hannesson, Stephen A.
              Weiss and the Company. (3)
*10.57        Registration Rights Agreement, dated November 13, 2000, among
              Mathers Associates, Klass Partners, Ltd., Jon Paul Hannesson,
              Stephen A. Weiss and the Company. (3)
*10.58        Dispute Resolution Management, Inc. Undertaking Letter dated
              November 13, 2000. (3)
*10.70        Conversion Notice, dated April 9, 2001 between S. Brewer
              Enterprises, Inc. and the Company for the conversion of $250,000
              of the Restated Brewer Note. (3)
*10.71        Memorandum of Understanding for Amendment of $500,000 CXI Bridge
              Loan Documents, dated April 16, 2001, by and among the Company,
              Commodore Environmental Services, Inc., Mathers Associates, Jon
              Paul Hannesson and Stephen A. Weiss. (3)
*10.72        Klass Partners Ltd. Agreement for Amendment of CXI Bridge Loan
              Documents, dated April 16, 2001, by the Company and Klass
              Partners, Ltd. (3)
*10.73        Warrant to purchase 300,000 shares of Common Stock of the Company
              issued to Mathers Associates. (3)

                                       28


*10.74        Warrant to purchase 75,000 shares of Common Stock of the Company
              issued to Jon Paul Hannesson. (3)
*10.75        Warrant to purchase 75,000 shares of Common Stock of the Company
              issued to Krista S. Hannesson. (3)
*10.76        Warrant to purchase 50,000 shares of Common Stock of the Company
              issued to Stephen A. Weiss. (3)
**5.1         Opinion of McGuireWoods, LLP.
**23.1        Consent of PricewaterhouseCoopers LLP.
*23.2         Consent of McGuireWoods, LLP (contained in Exhibit 5.1).
**23.3        Consent of Tanner + Co.
**23.4        Consent of Foote, Passey, Griffen & Co., LC




-----------------

*        Previously filed electronically.
**       Filed herewith electronically.


         1.   Incorporated herein by reference. Filed as an exhibit to the
              Company's Registration Statement on Form S-1 (Registration No.
              333-4396) filed with the Commission on May 2, 1996.

         2.   Incorporated herein by reference. Filed as an exhibit to the
              Company's Current Report on Form 8-K filed with the Commission on
              September 12, 2000.

         3.   Incorporated herein by reference. Filed as an exhibit to the
              Company's Annual Report on Form 10K/A (File No. 1-11871) filed
              with the Commission on May 04, 2001.


                                       29




                    SUBJECT TO COMPLETION, DATED MAY 04, 2001

PROSPECTUS

                                19,241,667 Shares

                      COMMODORE APPLIED TECHNOLOGIES, INC.

                                  Common Stock

                               -------------------

         The selling stockholders listed on page 12 of this prospectus are
selling these shares for their own accounts. These sales may be made either at
fixed prices which may be changed, at market prices prevailing at the time of
sale, at prices related to prevailing market prices or at negotiated prices.

         Our common stock is traded on the American Stock Exchange under the
symbol CXI.

                               -------------------

         Investing in the common stock involves a high degree of risk. See "Risk
Factors" beginning on page 2.

                               -------------------

         Neither the Securities and Exchange Commission nor any state securities
commission has approved or disapproved of these securities, or determined if
this prospectus is truthful or complete. Any representation to the contrary is a
criminal offense.



                               -------------------

                   The date of this prospectus is May 04, 2001



                                   Red Herring



The information in this prospectus is not complete and may be changed. These
securities may not be sold until the registration statement filed with the
Securities and Exchange Commission is effective. This prospectus is not an offer
to sell these securities and it is not soliciting an offer to buy these
securities in any state where the offer or sale is not permitted.

No one (including any salesman or broker) is authorized to provide oral or
written information about this offering that is not included in this prospectus.



                                       30