FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person *   Chondros Dimitrios 2. Date of Event Requiring Statement (Month/Day/Year) 05/02/2018 3. Issuer Name and Ticker or Trading Symbol HALOZYME THERAPEUTICS INC [HALO] (Last) (First) (Middle) C/O HALOZYME THERAPEUTICS, INC., 11388 SORRENTO VALLEY ROAD 4. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) SVP, Chief Medical Officer 5. If Amendment, Date Original Filed(Month/Day/Year) (Street) SAN DIEGO, CA 92121 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Beneficially Owned

1.Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5) Common Stock 34,076 (1) D Â

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.			SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Option to Purchase Common Stock	08/03/2016(2)	08/03/2025	Common Stock	100,000	$ 23.03	D	Â
Option to Purchase Common Stock	02/03/2017(2)	02/03/2026	Common Stock	41,841	$ 8.11	D	Â
Option to Purchase Common Stock	02/22/2018(2)	02/22/2027	Common Stock	24,861	$ 12.07	D	Â
Option to Purchase Common Stock	06/01/2018(3)	06/01/2027	Common Stock	13,218	$ 12.24	D	Â
Option to Purchase Common Stock	02/14/2019(3)	02/14/2028	Common Stock	47,635	$ 18.41	D	Â
Restricted Stock Units	02/22/2018(4)	  (4)	Common Stock	11,651	$ (4)	D	Â
Restricted Stock Units	02/14/2019(5)	  (5)	Common Stock	8,170	$ (5)	D	Â
Restricted Stock Units	02/14/2019(5)	  (5)	Common Stock	27,160	$ (5)	D	Â

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Chondros Dimitrios C/O HALOZYME THERAPEUTICS, INC. 11388 SORRENTO VALLEY ROAD SAN DIEGO, CA 92121	Â	Â	  SVP, Chief Medical Officer	Â

Signatures

/s/ James R. Oehler as attorney-in-fact for Dimitrios Chondros		05/07/2018
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Includes 7,500 shares of restricted stock that vest in equal pro rata amounts on August 3, 2018 and August 3, 2019. Also includes 12,330 shares of restricted stock that vest in equal pro rata amounts on February 3, 2019 and February 3, 2020.
(2)	This option vested one-fourth on such date and vests 1/48th monthly thereafter.
(3)	This option vests one-fourth on such date and then 1/48th monthly thereafter.
(4)	This award vested one-fourth on the first anniversary of the grant date and then one-fourth on each anniversary date thereafter. Represents a restricted stock unit award with no exercise price.
(5)	This award vests one-fourth on the first anniversary of the grant date and then one-fourth on each anniversary date thereafter. Represents a restricted stock unit award with no exercise price.
  Remarks: Exhibit List:  Exhibit 24 - Power of Attorney

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