UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 10-K/A

                                 Amendment No. 2
(Mark One)
[X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT
OF 1934

For the fiscal year ended July 31, 2001

[ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
ACT OF 1934

For the transition period from ____________ to _______________

                        Commission file number 000-25169

                        GENEREX BIOTECHNOLOGY CORPORATION
             -----------------------------------------------------
             (Exact name of registrant as specified in its charter)

             Delaware                             98-0178636
             --------                             ----------
    (State or other jurisdiction          (IRS Employer Identification No.)
  of incorporation or organization)

33 Harbour Square, Suite 202, Toronto, Canada        M5J2G2
---------------------------------------------        ------
  (Address of principal executive offices)         (Zip Code)

        Registrant's telephone number, including area code: 416/364-2551
           Securities registered pursuant to Section 12(b) of the Act:
                                      None

           Securities registered pursuant to section 12(g) of the Act:
                     Common Stock, par value $.001 per share
                                (Title of Class)

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such report(s), and (2) has been subject to such filing
requirements for the past 90 days.

                Yes [X] No [ ]

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405
of Regulation S-K is not contained herein, and will not be contained, to the
best of registrant's knowledge, in definitive proxy or information statements
incorporated by reference in Part III of this Form 10-K or any amendment to this
Form 10-K.      [X]

The aggregate market value of the voting stock held by non-affiliates of the
registrant at October 15, 2001, based on the closing price as of that date, was
approximately $64,625,733.

At October 15, 2001, the registrant had 20,682,634 shares of Common Stock
outstanding.

                    Documents incorporated by reference: None


         By this amendment, we hereby correct the list of Exhibits that was
contained in Item 14 of the Form 10-K that we filed with the Commission on
October 29, 2001. The following restates Item 14 in its entirety.

                                     PART IV

Item 14. Exhibits, Financial Statement Schedules and Reports on Form 8-K.

(a)  Exhibits

Exhibit No.                   Description
-----------                   -----------

3.1           Restated Certificate of Incorporation of Generex Biotechnology
              Corporation filed as Exhibit 3-1 to our Quarterly Report on Form
              10-Q for the quarter ended April 30, 1999 filed with the
              Commission on June 14, 1999 is incorporated herein by reference.

3.2           Bylaws of the Company filed as Exhibit 3.2 to our Registration
              Statement on Form S-1 (File No. 333-82667) filed with the
              Commission on July 12, 1999 ("1999 S-1") is incorporated herein by
              reference.

4.1.1         Form of common stock certificate filed as Exhibit 4.1 to our 1999
              S-1 is incorporated herein by reference.

4.1.2         Certificate of Designations, Preferences and Rights of Series A
              Preferred Stock filed as Exhibit 4.4 to our Report on Form 8-K
              filed with the Commission on January 23, 2001 ("January 2001 8-K")
              is incorporated herein by reference.

4.2.1         1998 Stock Option Plan filed as Exhibit 4.3 to our 1999 S-1 is
              incorporated herein by reference.

4.2.2         2000 Stock Option Plan filed as Exhibit 4.3.2 to our Form 10-K
              for the fiscal year ended July 31, 2000 filed with the Commission
              on October 30, 2000 is incorporated herein by reference.

4.2.3         2001 Stock Option Plan filed as Exhibit 4.2.3 to our Form 10-K
              for the fiscal year ended July 31, 2001 filed with the Commission
              on October 28, 2001 ("2001 10-K").

4.3           Form of Warrant issued to Ladenburg Thalmann & Co., Inc. dated
              July 6, 2001, filed as Exhibit 4.14 to our Registration Statement
              on Form S-3 (File No. 333-67118) filed with the Commission on
              August 8, 2001 is incorporated herein by reference.

4.4.1         Form of Securities Purchase Agreement entered into with Cranshire
              Capital, L.P.; RAM Trading Ltd.; Gryphon Master Fund; Kodiak
              Opportunity, L.P.; Kodiak Opportunity 3C7, L.P.; Kodiak
              Opportunity Offshore, Ltd.; Novelly Exempt Trust; Langley
              Partners, L.P.; Montrose Investments, Ltd.; WEC Asset Management,
              LLC; ZLP Master Technology Fund, Ltd.; Alpha Capital
              Aktiengesellschaft; and The dotCOM Fund, LLC, dated July 3, 2001,
              filed as Exhibit 1 to our Report on Form 8-K dated July 6, 2001
              and filed with the Commission on July 17, 2001 ("July 2001 8-K")
              is incorporated herein by reference.


4.4.2         Form of Registration Rights Agreement entered into with Cranshire
              Capital, L.P.; RAM Trading Ltd.; Gryphon Master Fund; Kodiak
              Opportunity, L.P.; Kodiak Opportunity 3C7, L.P.; Kodiak
              Opportunity Offshore, Ltd.; Novelly Exempt Trust; Langley
              Partners, L.P.; Montrose Investments, Ltd.; WEC Asset Management,
              LLC; ZLP Master Technology Fund, Ltd.; Alpha Capital
              Aktiengesellschaft; and The dotCOM Fund, LLC, dated July 3, 2001,
              filed as Exhibit 2 to our July 2001 8-K is incorporated herein by
              reference.

4.4.3         Form of Warrant granted to Cranshire Capital, L.P.; RAM Trading
              Ltd.; Gryphon Master Fund; Kodiak Opportunity, L.P.; Kodiak
              Opportunity 3C7, L.P.; Kodiak Opportunity Offshore, Ltd.; Novelly
              Exempt Trust; Langley Partners, L.P.; Montrose Investments, Ltd.;
              WEC Asset Management, LLC; ZLP Master Technology Fund, Ltd.; Alpha
              Capital Aktiengesellschaft; and The dotCOM Fund, LLC, dated July
              6, 2001, filed as Exhibit 3 to our July 2001 8-K is incorporated
              herein by reference.

4.5.1         Securities Purchase Agreement entered into with Capital Ventures
              International, dated July 3, 2001, filed as Exhibit 4 to our July
              2001 8-K is incorporated herein by reference.

4.5.2         Registration Rights Agreement entered into with Capital Ventures
              International, dated July 3, 2001, filed as Exhibit 5 to our July
              2001 8-K is incorporated herein by reference.

4.5.3         Warrant granted to Capital Ventures International, dated July 3,
              2001, filed as Exhibit 6 to our July 2001 8-K is incorporated
              herein by reference.

4.6.1         Form of Securities Purchase Agreement entered into with Elliott
              International, L.P. and Elliott Associates, L.P., dated July 3,
              2001, filed as Exhibit 7 to our July 2001 8-K is incorporated
              herein by reference.

4.6.2         Form of Registration Rights Agreement entered into with Elliott
              International, L.P. and Elliott Associates, L.P., dated July 3,
              2001, filed as Exhibit 8 to our July 2001 8-K is incorporated
              herein by reference.

4.6.3         Warrant issued to Elliott International, L.P. and Elliott
              Associates, L.P., dated July 5, 2001, filed as Exhibit 9 to our
              July 2001 8-K is incorporated herein by reference.

4.7.1         Securities Purchase Agreement between Generex Biotechnology
              Corporation, Elan International Services, Ltd. and Elan
              Corporation, plc., dated January 16, 2001, filed as Exhibit 4.1 to
              our Report on Form 8-K/A dated January 16, 2001 filed with the
              Commission on February 1, 2001 is incorporated herein by
              reference.

4.7.2         Registration Rights Agreement between Generex Biotechnology
              Corporation and Elan International Services, Ltd. dated January
              16, 2001 filed as Exhibit 4.2 to our January 2001 8-K is
              incorporated herein by reference.


4.7.3         Form of Warrant issued to Elan International Services, Ltd. filed
              as Exhibit 4.3 to our January 2001 8-K is incorporated herein by
              reference.

4.8.1         Form of Securities Purchase Agreement entered into with certain
              parties to October 2000 Private Placement filed as Exhibit 2 to
              our Report on Form 8-K dated October 4, 2000 and filed on October
              16, 2000 ("October 2000 8-K") is incorporated herein by reference.

4.8.2         Form of Registration Rights Agreement entered into with certain
              parties to October 2000 Private Placement filed as Exhibit 3 to
              our October 2000 8-K is incorporated herein by reference.

4.8.3         Form of Warrant issued to certain parties to October 2000 Private
              Placement filed as Exhibit 4 to our October 2000 8-K is
              incorporated herein by reference.

4.9           Securities Purchase Agreement entered into with Smallcap World
              Fund, Inc. dated September 29, 2000 filed as Exhibit 1 to our
              October 2000 8-K is incorporated herein by reference.

4.10          Form of Warrant (GCR Series) held by Robert P. Carter, Harvey
              Kaye, Fittube, Inc., Edward Maskaly and Gulfstream Capital Group,
              L.C. filed as Exhibit 4.4.2 to our Registration Statement on Form
              10 filed with the Commission December 14, 1998, as amended
              February 24, 1999 ("Form 10"), is incorporated herein by
              reference.

4.11          Letter Agreement and Warrant with M. H. Meyerson & Co., Inc. dated
              November 17, 1998 filed as Exhibit 4.4.4 to our Form 10 is
              incorporated herein by reference.

4.12          Option Agreement with Wolfe Axelrod Weinberger LLC dated January
              3, 2000, filed as Exhibit 4.5 to our Quarterly Report on Form 10-Q
              for the quarter ended January 31, 2000 filed with the Commission
              on March 14, 2000 is incorporated herein by reference.

10.1.1        Supplemental Agreement dated December 31, 2000 between Generex
              Pharmaceuticals, Inc., Generex Biotechnology Corporation and Dr.
              Pankaj Modi, filed as Exhibit 10.1.4 to our 2001 10-K.

10.1.2        Memorandum of Agreement dated January 7, 1998 between Generex
              Pharmaceuticals, Inc., GHI Inc., Generex Biotechnology
              Corporation, Dr. Pankaj Modi and Galaxy Technology, Canada, filed
              as Exhibit 10.1.3 to our 2001 10-K.

10.1.3        Assignment and Assumption Agreement with Pankaj Modi filed as
              Exhibit 10.1.2 to our our Registration Statement on Form 10/A
              filed with the Commission on February 24, 1999 is incorporated
              herein by reference

10.1.4        Consulting Agreement with Pankaj Modi filed as Exhibit 10.1.1 to
              our Form 10 is incorporated herein by reference.


10.2          Development and License Agreement dated September 5, 2000 between
              Generex Biotechnology Corporation and Eli Lilly and Company filed
              as Exhibit 10.1 to our Report on Form 8-K/A dated September 5,
              2000 and filed with the Commission on January 24, 2001 is
              incorporated herein by reference.

21            Subsidiaries of the Registrant, filed as Exhibit 21 to our 2001
              10-K.

23.1.1        Consent of Deloitte & Touche LLP, independent public accountants,
              filed as Exhibit 23.1.1 to our 2001 10-K.

23.1.2        Consent of WithumSmith+Brown, independent public accountants,
              filed as Exhibit 23.1.2 to our 2001 10-K.

24            Powers of Attorney, filed as Exhibit 24 to our 2001 10-K.

----------------

(b)      Reports on Form 8- K

         The following Reports on Form 8-K were filed during the last quarter of
the fiscal year:

1.       Report on Form 8-K, filed with the Commission on May 22, 2001,
         announcing an increase in the size of Generex's Board of Directors from
         six to seven members, the appointment of Ivan Lieberburg, Ph.D., M.D.
         as a director of Generex, and the removal of Generex from the Nasdaq
         Biotechnology Index.

2.       Report on Form 8-K, filed with the Commission on July 17, 2001,
         announcing two private placements completed on or about July 6, 2001 in
         which Generex raised $11,59,994.75 through the sale of units consisting
         of one share of common stock and a warrant to purchase .25 shares of
         common stock. The units were sold without registration under the
         Securities Act of 1933 in reliance upon the exemption from registration
         provided in Section 4(2) thereof and Rule 506 of Regulation D
         promulgated thereunder.

3.       Report on Form 8-K, filed with the Commission on August 15, 2001,
         announcing that Generex had entered into a termination agreement with
         Tradersbloom Limited pursuant to which the equity draw down facility
         was terminated.


                                   SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange
Act of 1934, the registrant has duly caused this Report to be signed by the
undersigned, thereunto duly authorized, this 27th day of February, 2002.

GENEREX BIOTECHNOLOGY CORPORATION

By: /s/ Anna E. Gluskin
    --------------------------
    Anna E. Gluskin, President



Pursuant to the requirements of the Securities Exchange Act of 1934, the Report
has been signed below by the following persons on behalf of the registrant and
in the capacities and on the dates indicated.



Name                                Capacity in which signed                       Date
----                                ------------------------                       ----
                                                                             
/s/ Anna E. Gluskin                 President, Chief Executive Officer             February 27, 2002
---------------------------         and Director
Anna E. Gluskin

/s/ E. Mark Perri                   Chairman, Chief Financial Officer              February 27, 2002
---------------------------         and Director
E. Mark Perri                       (principal financial and accounting officer)


/s/ Rose C. Perri                   Secretary, Treasurer, Chief Operating          February 27, 2002
---------------------------         Officer and Director
Rose C. Perri

/s/ Pankaj Modi*                    Vice President, Research and Development       February 27, 2002
---------------------------         and Director
Pankaj Modi

/s/ Michael Hawke*                  Director                                       February 27, 2002
---------------------------
Michael Hawke

/s/ Ivan M. Lieberburg*             Director                                       February 27, 2002
---------------------------
Ivan M. Lieberburg

/s/ Jan Michael Rosen*              Director                                       February 27, 2002
---------------------------
Jan Michael Rosen

*By /s/ E. Mark Perri
---------------------------
E. Mark Perri, as Attorney-in-fact