FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * BRYANT DOUGLAS C   2. Issuer Name and Ticker or Trading Symbol QUIDEL CORP /DE/ [QDEL] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) President & CEO (Last) (First) (Middle) 12544 HIGH BLUFF DRIVE, SUITE 200 3. Date of Earliest Transaction (Month/Day/Year) 03/27/2019 (Street) SAN DIEGO, CA 92130 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 03/27/2019   M   795 A $ 12.63 302,237 D   Common Stock 03/27/2019   S   795 D $ 65.03 (1) 301,442 D   Common Stock 03/28/2019   M   1,335 A $ 12.63 302,777 D   Common Stock 03/28/2019   S   1,335 D $ 65.062 (2) 301,442 D   Common Stock 03/29/2019   M   23,120 A $ 12.63 324,562 D   Common Stock 03/29/2019   S   23,120 D $ 65.696 (3) 301,442 D

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Non-Qualified Stock Option

$ 12.63

03/27/2019

M

795

(4)

03/02/2021

Common Stock

795

$ 0

30,293

D

Non-Qualified Stock Options

$ 12.63

03/28/2019

M

1,335

(4)

03/02/2021

Common Stock

1,335

$ 0

28,958

D

Non-Qualified Stock Options

$ 12.63

03/29/2019

M

23,120

(4)

03/02/2021

Common Stock

23,120

$ 0

5,838

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
BRYANT DOUGLAS C 12544 HIGH BLUFF DRIVE, SUITE 200 SAN DIEGO, CA 92130	X		President & CEO

Signatures

Robert J. Bujarski, attorney-in-fact for Douglas C. Bryant		03/29/2019
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The weighted average sale price for these transactions was $65.03 per share, with a range of $65.00 to $65.11. Upon request, the Reporting Person hereby undertakes to provide to staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder, the full information regarding the number of shares sold at each separate price.
(2)	The weighted average sale price for these transactions was $65.062 per share, with a range of $65.03 to $65.08. Upon request, the Reporting Person hereby undertakes to provide to staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder, the full information regarding the number of shares sold at each separate price.
(3)	The weighted average sale price for these transactions was $65.696 per share, with a range of $65.38 to $66.29. Upon request, the Reporting Person hereby undertakes to provide to staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder, the full information regarding the number of shares sold at each separate price.
(4)	42,959 shares vested on 03/02/2013; 21,479 shares vested on 03/02/2014; 21,480 shares vested on 03/02/2015.
Remarks: All transactions reported herein were effected pursuant to a pre-established 10b5-1 trading plan.

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