Free Writing Prospectus

Issuer Free Writing Prospectus

  Filed Pursuant to Rule 433
  Registration No. 333-150290
  May 20, 2008

Amgen Inc.

TERM SHEET

Dated May 20, 2008

$500,000,000   6.90% Senior Notes due 2038

This term sheet relates only to the securities described below and supplements and should be read together with the preliminary prospectus supplement, dated May 20, 2008 and the accompanying prospectus (including the documents incorporated by reference in the accompanying prospectus) relating to these securities.

 

Issuer:

   Amgen Inc.

Ranking:

   Senior Unsecured

Size:

   $500,000,000

Maturity Date:

   June 1, 2038

Coupon:

   6.900%

Price to Public:

   99.683%

Yield to Maturity:

   6.925%

Treasury Benchmark:

   5.000% due May 15, 2037

Spread to Benchmark:

   240 bps

Interest Payment Dates:

   June 1 and December 1, commencing December 1, 2008

Net Proceeds to Issuer:

   $494,040,000

Capitalization Table Items as of

March 31, 2008 (as adjusted):

   Cash, cash equivalents and marketable securities: $8,638
  

Floating Rate Notes: $1,000

2018 notes and 2038 notes offered hereby: $998

Total long-term debt: $10,175

Total capitalization: $30,262

Trade Date:

   May 20, 2008

Settlement Date:

   May 23, 2008 (T+3)

CUSIP:

   031162AY6

ISIN:

   US031162AY66

Denominations:

   $2,000 x $1,000

Ratings:

  

Moody’s: A3 (Stable Outlook)

S&P: A+ (Negative Outlook)

Fitch: A (Stable)

Underwriters:

   Joint Book-Running Managers:
   Goldman, Sachs & Co.
   Merrill Lynch, Pierce, Fenner & Smith Incorporated
   Barclays Capital Inc.
  

Co-Managers:

Banc of America Securities LLC

Citigroup Global Market Inc.

Credit Suisse Securities (USA) LLC

Deutsche Bank Securities Inc.

J.P. Morgan Securities Inc.

Lehman Brothers Inc.

Mitsubishi UFJ Securities International plc

Morgan Stanley & Co. Incorporated

Greenwich Capital Markets, Inc.

Daiwa Securities America Inc.

Amgen Inc. has filed a registration statement (including a prospectus dated as of April 17, 2008) and a prospectus supplement dated as of May 20, 2008 with the SEC for the offering to which this communication relates. Before you invest, you should read the prospectus in that registration statement, the prospectus supplement and other documents Amgen Inc. has filed with the SEC for more complete information about the issuer and this offering. You should rely on the prospectus, prospectus supplement and any relevant free writing prospectus or term sheet for complete details. You may get these documents for free by visiting the SEC Web site at www.sec.gov. Alternatively, copies of the prospectus and the prospectus supplement may be obtained from Goldman, Sachs & Co., Prospectus Department, by calling 866-471-2526, Merrill Lynch, Pierce, Fenner & Smith Incorporated by calling 866-500-5408 or Barclays Capital Inc. by calling 888-227-2275, Ext. 2663.

The security ratings above are not a recommendation to buy, sell or hold the securities offered hereby. The ratings may be subject to revision or withdrawal at any time by Moody’s, S&P and Fitch. Each of the security ratings above should be evaluated independently of any other security rating.