Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
HBM Healthcare Investments (Cayman) Ltd.
  2. Issuer Name and Ticker or Trading Symbol
Ophthotech Corp. [OPHT]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
GOVERNORS SQUARE, SUITE #4-212-2, 23 LIME TREE BAY AVE., WEST BAY
3. Date of Earliest Transaction (Month/Day/Year)
09/30/2013
(Street)

GRAND CAYMAN, E9 00000
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 09/30/2013   C   2,806,937 (4) A (1) 2,806,937 D  
Common Stock 09/30/2013   C   398,208 (5) A (2) 3,205,145 D  
Common Stock 09/30/2013   C   206,756 (6) A (3) 3,411,902 (9) D  
Common Stock 09/30/2013   P   228,000 A $ 22 3,639,902 D  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Series A Preferred Stock (1) 09/30/2013   C     2,806,937 (4)   (1)   (1) Common Stock 2,806,937 (4) (1) 0 D  
Series B Preferred Stock (2) 09/30/2013   C     398,208 (5)   (2)   (2) Common Stock 398,208 (5) (2) 0 D  
Series C Preferred Stock (3) 09/30/2013   C     206,756 (6)   (3)   (3) Common Stock 206,756 (6) (3) 0 D  
Series A Preferred Stock Warrant (7) 09/30/2013   C     13,670 (7)   (7) 06/18/2017 Common Stock 13,670 (7) $ 0 0 D  
Common Stock Warrant $ 0.059 09/30/2013   C   13,670 (7)     (8) 06/18/2017 Common Stock 13,670 (7) (7) 13,670 (7) D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
HBM Healthcare Investments (Cayman) Ltd.
GOVERNORS SQUARE, SUITE #4-212-2
23 LIME TREE BAY AVE., WEST BAY
GRAND CAYMAN, E9 00000
    X    

Signatures

 /s/ Jean-Marc Lesieur, Director   10/03/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Each share of Series A Preferred Stock automatically converted into Common Stock on a 1 for 5.9 reverse split basis upon the closing of the Issuer's firm commitment underwritten public offering pursuant to a registration statement on Form S-1 under the Securities Act of 1933, as amended (the "IPO") and had no expiration date.
(2) Each share of Series B Preferred Stock automatically converted into Common Stock on a 1 for 5.9 reverse split basis upon the closing of the Issuer's IPO and had no expiration date.
(3) Each share of Series C Preferred Stock automatically converted into Common Stock on a 1 for 5.9 reverse split basis upon the closing of the Issuer's IPO and had no expiration date.
(4) Includes 370,591 shares of Common Stock issued upon the closing of the Issuer's IPO for stock dividends that accrued on the Series A Preferred Stock prior to conversion.
(5) Includes 45,101 shares of Common Stock issued upon the closing of the Issuer's IPO for stock dividends that accrued on the Series B Preferred Stock prior to conversion.
(6) Includes 1,782 shares of Common Stock issued upon the closing of the Issuer's IPO for stock dividends that accrued on the Series C Preferred Stock prior to conversion.
(7) The Series A Preferred Stock Warrant converted to a Common Stock Warrant in connection with the closing of the Issuer's IPO. The number of shares of the Common Stock Warrant includes an adjustment to account for additional shares of Common Stock issued as accrued stock dividends in connection with the closing of the issuer's IPO.
(8) Immediately exercisable.
(9) Pursuant to the issuer's fourth amended and restated certificate of incorporation as amended, all shares of the Issuer's preferred stock were aggregated across series for purposes of conversion to Common Stock resulting in an additional whole share being issued as a result of the aggregation of fractional shares across series.

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