Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Harper Sean E
 2. Date of Event Requiring Statement (Month/Day/Year)
02/13/2012		 3. Issuer Name and Ticker or Trading Symbol
AMGEN INC [AMGN]
(Last)
(First)
(Middle)
ONE AMGEN CENTER DRIVE		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
EVP, Research & Development
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

THOUSAND OAKS, CA 91320-1799		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 42,150 (1)
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Iso (Right to Buy) 04/03/2010 04/03/2013 Common Stock 1,391 $ 71.88 D  
Nqso (Right to Buy) 04/03/2007(2) 04/03/2013 Common Stock 16,109 $ 71.88 D  
Nqso (Right to Buy) 02/08/2008(3) 02/08/2014 Common Stock 14,400 $ 69.78 D  
Nqso (Right to Buy) 04/29/2012 04/29/2015 Common Stock 6,000 $ 42.13 D  
Nqso (Right to Buy) 04/28/2012(4) 04/28/2016 Common Stock 16,000 $ 50.44 D  
Nqso (Right to Buy) 04/26/2012(5) 04/26/2020 Common Stock 24,000 $ 58.43 D  
Nqso (Right to Buy) 04/25/2013(6) 04/25/2021 Common Stock 21,000 $ 54.69 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Harper Sean E
ONE AMGEN CENTER DRIVE
THOUSAND OAKS, CA 91320-1799		       EVP, Research & Development  

Signatures

/s/ Sean E. Harper 02/15/2012
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These shares include the following Restricted Stock Units (RSUs) granted under the Company's equity plans: 5,450 RSUs which fully vest on 4/29/2012; 2,250 RSUs which vest in two equal annual installments of 1,125 each commencing 4/28/2012; 3,450 RSUs which vest in three equal annual installments of 1,150 each commencing 4/26/2012; 25,000 RSUs which fully vest on 12/31/2014; and 6,000 RSUs which vest in two equal installments of 1,980 each on 4/25/2013 and 4/25/2014 and one installment of 2,040 on 4/25/2015. Vested RSUs will be paid in shares of the Company's common stock on a one-to-one basis.
(2) These stock options were fully exercisable on April 3, 2010.
(3) These stock options were fully exercisable on February 8, 2011.
(4) These stock options are exercisable in two annual installments of 8,000 each commencing 4/28/2012.
(5) These stock options are exercisable in three annual installments of 8,000 each commencing 4/26/2012.
(6) These stock options are exercisable in three annual installments of 33%, 33% and 34% on 4/25/2013, 4/25/2014 and 4/25/2015, respectively.

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