1

   AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON FEBRUARY 21, 2001

                                                     REGISTRATION NO.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                            ------------------------

                                    FORM S-3
                             REGISTRATION STATEMENT
                                     UNDER
                           THE SECURITIES ACT OF 1933
                            ------------------------

                              CISCO SYSTEMS, INC.
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)


                                              
                   CALIFORNIA                                       77-0059951
        (STATE OR OTHER JURISDICTION OF                          (I.R.S. EMPLOYER
         INCORPORATION OR ORGANIZATION)                       IDENTIFICATION NUMBER)


                             170 WEST TASMAN DRIVE
                           SAN JOSE, CALIFORNIA 95134
                                 (408) 526-4000
    (ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING AREA CODE,
                  OF REGISTRANT'S PRINCIPAL EXECUTIVE OFFICES)

                                JOHN T. CHAMBERS
                     PRESIDENT AND CHIEF EXECUTIVE OFFICER

                              CISCO SYSTEMS, INC.
                             300 EAST TASMAN DRIVE
                           SAN JOSE, CALIFORNIA 95134
                                 (408) 526-4000
  (NAME AND ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING AREA
                          CODE, OF AGENT FOR SERVICE)

                                    COPY TO:
                              MARK E. BETZEN, P.C.
                        BROBECK, PHLEGER & HARRISON LLP
                             TWO EMBARCADERO PLACE
                                 2200 GENG ROAD
                          PALO ALTO, CALIFORNIA 94303
                                 (650) 424-0160

        APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE TO THE PUBLIC:
     From time to time after this registration statement becomes effective.

    If the only securities being registered on this Form are being offered
pursuant to dividend or interest reinvestment plans, please check the following
box.  [ ]

    If any of the securities being registered on this Form are to be offered on
a delayed or continuous basis pursuant to Rule 415 under the Securities Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box.  [X]

    If this Form is filed to register additional securities for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list the Securities Act registration statement number of the earlier
effective registration statement for the same offering.  [ ]  __________

    If this Form is a post-effective amendment filed pursuant to Rule 462(c)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering.  [ ]  __________

    If delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box.  [ ]

                        CALCULATION OF REGISTRATION FEE



---------------------------------------------------------------------------------------------------------------------------
---------------------------------------------------------------------------------------------------------------------------
       TITLE OF EACH                 AMOUNT             PROPOSED MAXIMUM        PROPOSED MAXIMUM           AMOUNT OF
    CLASS OF SECURITIES              TO BE             AGGREGATE OFFERING          AGGREGATE              REGISTRATION
     TO BE REGISTERED              REGISTERED          PRICE PER SHARE(2)       OFFERING PRICE                FEE
---------------------------------------------------------------------------------------------------------------------------
                                                                                               
Common Stock, $0.001 par
  value per share(1).......          711,046               $27.38               $19,468,439.48             $4,867.11
---------------------------------------------------------------------------------------------------------------------------
---------------------------------------------------------------------------------------------------------------------------


(1) Includes associated rights to purchase shares of Series A Junior
    Participating Preferred Stock, par value $0.001 per share, of Cisco
    Systems, Inc.

(2) The price of $27.37, the average of the high and low prices of Cisco's
    common stock on The Nasdaq National Market on February 20, 2001, is set
    forth solely for the purpose of computing the registration fee pursuant to
    Rule 457(c).

     THE REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON SUCH DATE OR
DATES AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT SHALL
FILE A FURTHER AMENDMENT WHICH SPECIFICALLY STATES THAT THIS REGISTRATION
STATEMENT SHALL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE WITH SECTION 8(a) OF
THE SECURITIES ACT OF 1933, AS AMENDED, OR UNTIL THE REGISTRATION STATEMENT
SHALL BECOME EFFECTIVE ON SUCH DATE AS THE SECURITIES AND EXCHANGE COMMISSION,
ACTING PURSUANT TO SAID SECTION 8(a), MAY DETERMINE.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
   2

THE INFORMATION CONTAINED IN THIS PRELIMINARY PROSPECTUS IS NOT COMPLETE AND MAY
BE CHANGED. THESE SECURITIES MAY NOT BE SOLD UNTIL THE REGISTRATION STATEMENT
FILED WITH THE SECURITIES AND EXCHANGE COMMISSION IS EFFECTIVE. THIS PROSPECTUS
IS NOT AN OFFER TO SELL THESE SECURITIES AND IT IS NOT SOLICITING AN OFFER TO
BUY THESE SECURITIES IN ANY STATE WHERE THE OFFER OR SALE IS NOT PERMITTED.

                 SUBJECT TO COMPLETION, DATED FEBRUARY 21, 2001

PRELIMINARY PROSPECTUS

                                 711,046 Shares

                              CISCO SYSTEMS, INC.

                                  Common Stock

     The 711,046 shares of our common stock offered by this prospectus were
originally issued by us to the former shareholders of Netiverse, Inc. in
connection with our acquisition of Netiverse, Inc. All of the shares may be
resold from time to time by the holders of shares.

     The prices at which the shareholders may sell the shares will be determined
by the prevailing market price for shares of our common stock or in negotiated
transactions. We will not receive any of the proceeds from the sale of the
shares.

     Our common stock is quoted on The Nasdaq National Market under the symbol
"CSCO." On February 20, 2001, the last sale price of our common stock as
reported on The Nasdaq National Market was $26.0625.

     INVESTING IN OUR COMMON STOCK INVOLVES RISKS. SEE THE SECTIONS ENTITLED
"RISK FACTORS" IN THE DOCUMENTS WE FILE WITH THE SECURITIES AND EXCHANGE
COMMISSION THAT ARE INCORPORATED BY REFERENCES IN THIS PROSPECTUS FOR CERTAIN
RISKS AND UNCERTAINTIES THAT YOU SHOULD CONSIDER.

                           -------------------------

     NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES
COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR PASSED UPON THE
ADEQUACY OR ACCURACY OF THIS PROSPECTUS. ANY REPRESENTATION TO THE CONTRARY IS A
CRIMINAL OFFENSE.

                           -------------------------

               The date of this prospectus is February __, 2001.
   3

                                TABLE OF CONTENTS




                                                            PAGE
                                                            ----
                                                         
            Where You Can Find More Information...............1
            Incorporation of Certain Documents by Reference...1
            The Company.......................................2
            Plan of Distribution..............................2
            Selling Shareholders..............................5
            Use of Proceeds...................................6
            Legal Matters.....................................6
            Experts...........................................6


                      WHERE YOU CAN FIND MORE INFORMATION

     We file annual, quarterly and special reports, proxy statements and other
information with the Securities and Exchange Commission. You may read and copy
any reports, statements, or other information that we file at the Securities and
Exchange Commission's Public Reference Room at 450 Fifth Street, N.W.,
Washington, D.C. 20549. Please call the Securities and Exchange Commission at
1-800-SEC-0330 for further information on the operation of the Public Reference
Room. Our Securities and Exchange Commission filings are also available to the
public at our web site at http://www.cisco.com and at the Securities and
Exchange Commission's web site at http://www.sec.gov.

                INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

     The Securities and Exchange Commission allows us to "incorporate by
reference" the information we file with it, which means that we can disclose
important information to you by referring you to those documents. The
information incorporated by reference is considered to be part of this
prospectus except for any information superseded by information contained
directly in this prospectus or in later filed documents incorporated by
reference in this prospectus. We incorporate by reference the documents listed
below and any future filings made with the Securities and Exchange Commission
under Section 13(a), 13(c), 14, or 15(d) of the Securities Exchange Act of 1934
after the date of this prospectus and prior to the time all of the securities
offered by this prospectus are sold.

          (a) Our Annual Report on Form 10-K for the fiscal year ended July 29,
     2000;

          (b) Our Quarterly Report on Form 10-Q for the quarter ended October
     28, 2000;

          (c) Our Current Reports on Form 8-K filed on December 15, 1999 (as
     amended on Form 8-K/A filed on February 3, 2000 and on Form 8-K/A-1 filed
     on August 4, 2000), August 15, 2000, September 7, 2000, September 15, 2000,
     September 26, 2000, September 28, 2000, September 29, 2000, November 6,
     2000, November 7, 2000, November 13, 2000, November 15, 2000, December 19,
     2000, December 21, 2000, December 27, 2000, February 7, 2001, February 8,
     2001 and February 20, 2001;

          (d) The description of our common stock contained in our registration
     statement on Form 8-A filed January 11, 1990, including any amendments or
     reports filed for the purpose of updating such description; and

          (e) The description of our preferred stock purchase rights, contained
     in our registration statement on Form 8-A filed on June 11, 1998, including
     any amendments or reports filed for the purpose of updating such
     description.

                                        1
   4

     You may request a copy of these filings, at no cost, by writing or
telephoning us at the following address:
        Investor Relations
        Cisco Systems, Inc.
        170 West Tasman Drive
        San Jose, CA 95134-1706
        408-526-4000

     You should rely only on the information incorporated by reference or
provided in this prospectus or any prospectus supplement. We have not authorized
anyone to provide you with different information. We are not making an offer of
these securities in any state where the offer is not permitted. You should not
assume that the information in this prospectus or any prospectus supplement is
accurate as of any date other than the date on the front of this Prospectus.

                                  THE COMPANY

     Our principal executive offices are located at 170 West Tasman Drive,
San Jose, California 95134-1706. Our telephone number is (408) 526-4000.

                              PLAN OF DISTRIBUTION

     We are registering all 711,046 shares on behalf of the selling
shareholders. The selling shareholders named in the table below or pledgees,
donees, transferees or other successors-in-interest selling shares received from
a named selling shareholder as a gift, partnership distribution or other
non-sale-related transfer after the date of this prospectus may sell the shares
from time to time. The selling shareholders may also decide not to sell all the
shares they are allowed to sell under this prospectus. The selling shareholders
will act independently of us in making decisions with respect to the timing,
manner and size of each sale. The sales may be made on one or more exchanges or
in the over-the-counter market or otherwise, at prices and at terms then
prevailing or at prices related to the then current market prices, or in
negotiated transactions. The selling shareholders may effect such transactions
by selling the shares to or through broker-dealers. The shares may be sold
by one or more of, or a combination of, the following:

     - a block trade in which the broker-dealer so engaged will attempt to sell
       shares as agent but may position and resell a portion of the block as
       principal to facilitate the transaction;

     - purchases by a broker-dealer as principal and resale by such
       broker-dealer for its account pursuant to this prospectus;

     - an exchange distribution in accordance with the rules of such exchange;

                                        2
   5

     - ordinary brokerage transactions and transactions in which the broker
       solicits purchasers; and

     - privately negotiated transactions.

     To the extent required, this prospectus may be amended or supplemented from
time to time to describe a specific plan of distribution. In effecting sales,
broker-dealers engaged by the selling shareholders may arrange for other
broker-dealers to participate in the resales.

     The selling shareholders may enter into hedging transactions with
broker-dealers in connection with distributions of shares or otherwise. In such
transactions, broker-dealers may engage in short sales of shares in the course
of hedging the positions they assume with selling shareholders. The selling
shareholders also may sell shares short and redeliver shares to close out such
short positions. The selling shareholders may enter into option or other
transactions with broker-dealers which require the delivery of shares to the
broker-dealer. The broker-dealer may then resell or otherwise transfer such
shares pursuant to this prospectus. The selling shareholders also may loan or
pledge shares to a broker-dealer. The broker-dealer may sell the shares so
loaned, or upon a default the broker-dealer may sell the shares so pledged,
pursuant to this prospectus.

     Broker-dealers or agents may receive compensation in the form of
commissions, discounts or concessions from selling shareholders. Broker-dealers
or agents may also receive compensation from the purchasers of shares for whom
they act as agents or to whom they sell as principals, or both. Compensation as
to a particular broker-dealer might be in excess of customary commissions and
will be in amounts to be negotiated in connection with transactions involving
shares. Broker-dealers or agents and any other participating broker-dealers or
the selling shareholders may be deemed to be "underwriters" within the meaning
of Section 2(11) of the Securities Act of 1933 in connection with sales of
shares. Accordingly, any such commission, discount or concession received by
them and any profit on the resale of shares purchased by them may be deemed to
be underwriting discounts or commissions under the Securities Act of 1933.
Because selling shareholders may be deemed to be "underwriters" within the
meaning of Section 2(11) of the Securities Act of 1933, the selling shareholders
will be subject to the prospectus delivery requirements of the Securities Act of
1933. In addition, any shares covered by this prospectus which qualify for sale
pursuant to Rule 144 promulgated under the Securities Act of 1933 may be sold
under Rule 144 rather than pursuant to this prospectus. The selling shareholders
have advised us that they have not entered into any agreements, understandings
or arrangements with any underwriters or broker-dealers regarding the sale of
their shares.

     The shares may be sold only through registered or licensed brokers or
dealers if required under applicable state securities laws. In addition, in
certain states the shares may not be sold unless they have been registered or
qualified for sale in the applicable state or an exemption from the registration
or qualification requirement is available and is complied with.

     Under applicable rules and regulations under the Exchange Act of 1934, any
person engaged in the distribution of shares may not simultaneously engage in
market making activities with respect to our common stock for a period of two
business days prior to the commencement of such distribution. In addition, each
selling shareholder will be subject to applicable provisions of the Exchange Act
of 1934 and the associated rules and regulations under the Exchange Act of 1934,
including Regulation M, which provisions may limit the timing of purchases and
sales of shares of our common stock by the selling shareholders. We will make
copies of this prospectus available to the selling shareholders and have
informed them of the need for delivery of copies of this prospectus to
purchasers at or prior to the time of any sale of the shares.

     We will file a supplement to this prospectus, if required, pursuant to Rule
424(b) under the Securities Act of 1933 upon being notified by a selling
shareholder that any material arrangement has been entered into with a
broker-dealer for the sale of shares through a block trade, special offering,

                                        3
   6

exchange distribution or secondary distribution or a purchase by a broker or
dealer. Such supplement will disclose:

     - the name of each such selling shareholder and of the participating
       broker-dealer(s);

     - the number of shares involved;

     - the price at which such shares were sold;

     - the commissions paid or discounts or concessions allowed to such
       broker-dealer(s), where applicable;

     - that such broker-dealer(s) did not conduct any investigation to verify
       the information set out or incorporated by reference in this prospectus;
       and

     - other facts material to the transaction.

     We will bear all costs, expenses and fees in connection with the
registration of the shares. The selling shareholders will bear all commissions
and discounts, if any, attributable to the sales of the shares. The selling
shareholders may agree to indemnify any broker-dealer or agent that participates
in transactions involving sales of the shares against certain liabilities,
including liabilities arising under the Securities Act.

                                        4
   7

                              SELLING SHAREHOLDERS

     The following table sets forth the number of shares owned by each of the
selling shareholders. None of the selling shareholders has had a material
relationship with us within the past three years other than as a result of the
ownership of our common stock or other securities of ours or as a result of
their employment with us as of the date of the closing of the acquisition of
Netiverse, Inc. No estimate can be given as to the amount of our common stock
that will be held by the selling shareholders after completion of this offering
because the selling shareholders may offer all, some or none of their shares.
The shares offered by this prospectus may be offered from time to time by the
selling shareholders named below.




                                                NUMBER OF                                 NUMBER OF
                                                 SHARES            PERCENT OF              SHARES
                                              BENEFICIALLY         OUTSTANDING          REGISTERED FOR
NAME OF SELLING SHAREHOLDER                      OWNED               SHARES              SALE HEREBY
------------------------------------------------------------------------------------------------------------
                                                                                  
Cassidy Bridget A.                                2,202                  *                    2,202
Chanak, John A.                                  37,880                  *                   37,880
Chanak, Michael James                             1,761                  *                    1,761
Chou, Wesley S.                                   8,808                  *                    8,808
Colbert, Robert J.                                5,285                  *                    5,285
DeSantis Samuel R.                                  440                  *                      440
Egbert, Chandan                                  19,821                  *                   19,821
Farley, Rebecca                                  13,214                  *                   13,214
Fenton, John C.                                  24,665                  *                   24,665
Fredericks, Keith A.                              5,285                  *                    5,285
Han, xiaoping                                    17,618                  *                   17,618
Hayes, Kenneth A.                                 7,047                  *                    7,047
Hoch, Margot                                        991                  *                      991
Hubenthal, Mahlon                                 8,809                  *                    8,809
Knight, Joanne                                      590                  *                      590
LeRoy, Clinton                                      991                  *                      991
LeRoy, David J.                                  37,660                  *                   37,660
Majee, Sumandra                                   8,809                  *                    8,809
Marrero, Noel M.                                 12,333                  *                   12,333
Mathison, Paul T.                                 3,523                  *                    3,523
McCormack, Kathleen E.                            3,964                  *                    3,964
Metcalf, Jillian K                                4,404                  *                    4,404
Moen, Daniel G.                                   5,284                  *                    5,284
Nelson, Jeffrey                                     528                  *                      528
Nelson, Richard                                     528                  *                      528
Nelson, Teresa                                      528                  *                      528
Nelson, William M                                38,056                  *                   38,056
Nguyen, Anh Tien                                 17,618                  *                   17,618
Peterson, Gregg                                  17,618                  *                   17,618
Rao, Anantha                                        991                  *                      991
Rao, Gattupalli S.                               18,057                  *                   18,057
Rao, Nandini R.                                   3,523                  *                    3,523
Redmore, Josh                                       991                  *                      991
Redmore, Seth S.                                 37,660                  *                   37,660
Schoonmaker, Allen H.                             5,285                  *                    5,285
Sequoia Capital Entrepreneurs Fund               20,261                  *                   20,261
Sequoia Capital IX                              131,629                  *                  131,629
Sequoia Capital IX Principals Fund               24,296                  *                   24,296
Singh, Gururaj                                   88,093                  *                   88,093
Smith, Marshall                                     886                  *                      886
Strawn, Gary A.                                   7,047                  *                    7,047
Stuppi LLC                                       11,011                  *                   11,011
Truon, Hung Q.                                    4,404                  *                    4,404
Waterman, Alexander S.                           38,541                  *                   38,541
Waterman, Robert S.                                 660                  *                      660
Westphal, Christian J.                            6,166                  *                    6,166
Yim, Derrick                                      5,285                  *                    5,285
                                                -------                                     -------
                                                711,046                                     711,046


-------------------------
 *  Represents beneficial ownership of less than one percent.


                                        5


   8
                                USE OF PROCEEDS

     We will not receive any proceeds from the sale of the shares by the selling
shareholders.


                                 LEGAL MATTERS

     The validity of the shares offered hereby will be passed upon for us by
Brobeck, Phleger & Harrison LLP, Palo Alto, California.

                                    EXPERTS

     Our consolidated financial statements incorporated in this prospectus by
reference to our Annual Report on Form 10-K for the year ended July 29, 2000,
have been so incorporated in reliance on the report of PricewaterhouseCoopers
LLP, independent accountants, given on the authority of said firm as experts in
accounting and auditing.

     PricewaterhouseCoopers LLP ("PWC"), our independent accountants, has
notified us that PWC is engaged in discussions with the Securities and Exchange
Commission following an internal review by PWC, pursuant to an administrative
settlement with the Securities and Exchange Commission, of PWC's compliance with
auditor guidelines. PWC has advised us that we are one of the companies affected
by such discussions. We are not involved in the discussions between the
Securities and Exchange Commission and PWC and cannot predict the result of
those discussions.

                                        6
   9

================================================================================

We have not authorized any person to make a statement that differs from what is
in this prospectus. If any person does make a statement that differs from what
is in this prospectus, you should not rely on it. This prospectus is not an
offer to sell, nor is it seeking an offer to buy, these securities in any state
in which the offer or sale is not permitted. The information in this prospectus
is complete and accurate as of its date, but the information may change after
that date.




================================================================================

                               CISCO SYSTEMS, INC.



                                 711,046 SHARES
                                 OF COMMON STOCK



                                  ------------
                                   PROSPECTUS
                                  ------------






                               February __, 2001


================================================================================
   10

                                    PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS

ITEM 14. OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION

     The following table sets forth the costs and expenses, other than
underwriting discounts and commissions, payable by us in connection with the
sale of common stock being registered. All amounts are estimates except the
Securities and Exchange Commission registration fee.


                                                           
Securities and Exchange Commission Registration Fee.........   $ 4,867.11
Legal Fees and Expenses.....................................    15,000.00
Accounting Fees and Expenses................................     5,000.00
Printing Fees...............................................     5,000.00
Transfer Agent Fees.........................................     5,000.00
Miscellaneous...............................................    11,000.00
                                                               ----------
  Total.....................................................   $45,867.11
                                                               ==========


ITEM 15. INDEMNIFICATION OF DIRECTORS AND OFFICERS

     Section 317 of the California Corporations Code authorizes a court to
award, or a corporation's Board of Directors to grant, indemnity to directors
and officers in terms sufficiently broad to permit indemnification, including
reimbursement of expenses incurred, under certain circumstances for liabilities
arising under the Securities Act of 1933. Our Restated Articles of
Incorporation, and Bylaws provide for indemnification of our directors,
officers, employees and other agents to the maximum extent permitted by the
California Corporations Code. In addition, we have entered into indemnification
agreements with each of our directors and officers.

ITEM 16. EXHIBITS


         
     4.1    Restated Articles of Incorporation of Cisco Systems, Inc., as
            currently in effect
     4.2    Amended and Restated Bylaws of Cisco Systems, Inc., as currently in
            effect
     4.3    Rights Agreement between Cisco Systems, Inc. and Bank Boston, N.A.,
            dated as of June 10, 1998, as amended (incorporated by reference to
            our Current Report on Form 8-K filed on June 11, 1998 and our Annual
            Report on Form 10-K for the fiscal year ended July 29, 2000 filed on
            September 29, 2000)
     5.1    Opinion of Brobeck, Phleger & Harrison LLP
    23.1    Consent of PricewaterhouseCoopers LLP, Independent Accountants
    23.2    Consent of Brobeck, Phleger & Harrison LLP (included in Exhibit 5.1)
    24.1    Power of Attorney (included on Page II-3 of this
            registration statement)


ITEM 17. UNDERTAKINGS

A.   The Registrant hereby undertakes:

          (1) To file, during any period in which offers or sales are being
     made, a post-effective amendment to this Registration Statement:

               (i)   To include any prospectus required by Section 10(a)(3) of
          the Securities Act;

               (ii)  To reflect in the prospectus any facts or events arising
          after the effective date of the Registration Statement (or the most
          recent post-effective amendment thereof) which, individually or in the
          aggregate, represent a fundamental change in the information set
          forth in the Registration Statement; and

               (iii) To include any material information with respect to the
          plan of distribution not previously disclosed in this Registration
          Statement or any material change to such information in this
          Registration Statement;

     provided, however, that paragraphs (A) (1) (i) and (A) (1) (ii) do not
     apply if the information required to be included in a post-effective
     amendment by those paragraphs is contained in periodic reports filed by the
     Registrant pursuant to Section 13 or Section 15(d) of the Exchange Act that
     are incorporated by reference in this Registration Statement;

          (2) That, for the purpose of determining any liability under the
     Securities Act, each such post-effective amendment shall be deemed to be a
     new registration statement relating to the securities offered therein, and
     the offering of such securities at that time shall be deemed to be the
     initial bona fide offering thereof; and

          (3) To remove from registration by means of a post-effective amendment
     any of the securities being registered which remain unsold at the
     termination of the offering.

B.   The Registrant hereby undertakes that, for purposes of determining any
liability under the Securities Act, each filing of the annual report pursuant
to Section 13(a) or Section 15(d) of the Exchange Act that is incorporated by
reference in this Registration Statement shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

C.   Insofar as indemnification for liabilities arising under the Securities
Act may be permitted to directors, officers and controlling persons of the
Registrant pursuant to the foregoing provisions, or otherwise, the Registrant
has been advised that in the opinion of the Commission such indemnification is
against public policy as expressed in the Securities Act and is, therefore,
unenforceable. In the event that a claim for indemnification against such
liabilities (other than the payment by the Registrant of expenses incurred or
paid by a director, officer or controlling person of the Registrant in the
successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the
matter has been settled by controlling precedent, submit to a court of
appropriate jurisdiction the question whether such indemnification by it is
against public policy as expressed in the Securities Act and will be governed
by the final adjudication of such issue.




                                      II-1
   11

          (3) To remove from registration by means of a post-effective amendment
     any of the securities being registered which remain unsold at the
     termination of the offering.

     Insofar as indemnification for liabilities arising under the Securities Act
of 1933 may be permitted to directors, officers and controlling persons of the
registrant pursuant to the foregoing provisions or otherwise, we have been
advised that in the opinion of the Securities and Exchange Commission such
indemnification is against public policy as expressed in the Securities Act of
1933 and therefore is unenforceable. In the event that a claim for
indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, we will, unless in the opinion
of our counsel the matter has been settled by controlling precedent, submit to a
court of appropriate jurisdiction the question whether such indemnification by
it is against public policy as expressed in the Securities Act of 1933 and will
be governed by the final adjudication of such issue.

     The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act of 1933, each filing of the
registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Securities Exchange Act of 1934, and, where applicable, each filing of an
employee benefit plan's annual report pursuant to Section 15(d) of the
Securities Exchange Act of 1934, that is incorporated by reference in the
registration statement shall be deemed to be a new registration statement
relating to the securities offered therein, and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.



                                      II-2
   12

                                   SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, as amended, the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-3 and has duly caused this registration
statement to be signed on its behalf by the undersigned, thereunto duly
authorized in the City of San Jose, State of California, on this 21st day of
February, 2001.

                                          CISCO SYSTEMS, INC.

                                          By      /s/ JOHN T. CHAMBERS
                                            ------------------------------------
                                                      John T. Chambers
                                                 President, Chief Executive
                                                    Officer and Director

     KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears
below constitutes and appoints Larry R. Carter as his true and lawful
attorney-in-fact and agent, with full power of substitution and resubstitution,
for him and in his name, place and stead, in any and all capacities, to sign any
and all amendments (including post-effective amendments) to this registration
statement, and to file same, with all exhibits thereto, and other documents in
connection therewith, with the Securities and Exchange Commission, granting unto
said attorney-in-fact and agent full power and authority to do and perform each
and every act and thing requisite and necessary to be done in connection
therewith, as fully to all intents and purposes as he might or could do in
person, hereby ratifying and confirming all that said attorney-in-fact and agent
or his substitutes, may lawfully do or cause to be done by virtue thereof.

     Pursuant to the requirements of the Securities Act of 1933, as amended,
this registration statement has been signed below by the following persons on
behalf of Cisco and in the capacities and on the dates indicated:



                SIGNATURES                                    TITLE                         DATE
                ----------                                    -----                         ----
                                                                                 
           /s/ JOHN T. CHAMBERS              President, Chief Executive Officer and    February 21, 2001
------------------------------------------   Director (Principal Executive Officer)
             John T. Chambers

           /s/ LARRY R. CARTER                 Senior Vice President, Finance and      February 21, 2001
------------------------------------------   Administration, Chief Financial Officer,
             Larry R. Carter                    Secretary and Director (Principal
                                                Financial and Accounting Officer)

          /s/ JOHN P. MORGRIDGE                Chairman of the Board and Director      February 21, 2001
------------------------------------------
            John P. Morgridge

         /s/ DONALD T. VALENTINE                   Vice Chairman and Director          February 21, 2001
------------------------------------------
           Donald T. Valentine

           /s/ JAMES F. GIBBONS                             Director                   February 21, 2001
------------------------------------------
             James F. Gibbons

            /s/ STEVEN M. WEST                              Director                   February 21, 2001
------------------------------------------
              Steven M. West

           /s/ EDWARD R. KOZEL                              Director                   February 21, 2001
------------------------------------------
             Edward R. Kozel


                                      II-3
   13



                SIGNATURES                                    TITLE                        DATE
                ----------                                    -----                        ----
                                                                                 
            /s/ CAROL A. BARTZ                              Director                   February 21, 2001
------------------------------------------
              Carol A. Bartz

           /s/ JAMES C. MORGAN                              Director                   February 21, 2001
------------------------------------------
             James C. Morgan

             /s/ MARY CIRILLO                               Director                   February 21, 2001
------------------------------------------
               Mary Cirillo

              /s/ ARUN SARIN                                Director                   February 21, 2001
------------------------------------------
                Arun Sarin

             /s/ JERRY YANG                                 Director                   February 21, 2001
------------------------------------------
                Jerry Yang

             /s/ CARLY FIORINA                              Director                   February 21, 2001
------------------------------------------
                CARLY FIORINA




                                      II-4
   14
                               INDEX TO EXHIBITS



EXHIBIT
NUMBER                           EXHIBIT TITLE
-------                          -------------
      
  4.1    Restated Articles of Incorporation of Cisco Systems, Inc., as currently
         in effect
  4.2    Amended and Restated Bylaws of Cisco Systems, Inc., as currently in
         effect
  4.3    Rights Agreement between Cisco Systems, Inc. and Bank Boston, N.A.,
         dated as of June 10, 1998, as amended  (incorporated by reference to
         our Current Report on Form 8-K filed on June 11, 1998 and our Annual
         Report on Form 10-K for the fiscal year ended July 29, 2000, filed
         September 29, 2000)
  5.1    Opinion of Brobeck, Phleger & Harrison LLP
 23.1    Consent of PricewaterhouseCoopers LLP, Independent Accountants
 23.2    Consent of Brobeck, Phleger & Harrison LLP (included in Exhibit 5.1)
 24.1    Power of Attorney (included on Page II-3 of this
         registration statement)